mTOR-related linc-PMB promotes mitochondrial biogenesis via stabilizing SIRT1 mRNA through binding to the HuR protein

mTOR-related linc-PMB promotes mitochondrial biogenesis via stabilizing SIRT1 mRNA through binding to the HuR protein

Mitochondrial dysfunction is implicated in numerous disorders, including type 2 diabetes, Alzheimer’s disease and cancer. Long non-coding RNAs (lncRNAs) are emerging as pivotal regulators of cellular energy metabolism, yet their roles remai...

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Bibliographic Details
Main Authors: Chen Qian, Zhang Huaying, Wang Daokun, Liao Wenjing, Liu Yazhou, Cai Yurui, Wang Siyou, Yu Mengqian
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-01-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
HuR
long non-coding RNA
mitochondrial biogenesis
mTOR
SIRT1
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024236
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