Janus kinase inhibitors in palmoplantar pustulosis: a mixed-methods feasibility (JAKPPPOT) trial protocol

Janus kinase inhibitors in palmoplantar pustulosis: a mixed-methods feasibility (JAKPPPOT) trial protocol

Background Palmoplantar pustulosis (PPP) is a rare, debilitating inflammatory skin disease involving painful pustules on the palms and soles. Janus kinase (JAK) inhibitors target pathways relevant to PPP disease biology but also confer a risk of major adverse cardiovascular events and malignancy in...

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Main Authors: Weiyu Ye, Suzie Cro, James B Galloway, Sarah Chapman, C H Smith, Kingsley Powell, Jonathan Barker, Ann Naylor, Helen McAteer, John Gregory, David Gleeson, April Qin, Jade Pizzato, Manpreet K Sagoo, Lucy Moorhead, Andrew E Pink, Richard Woolf, Satveer K Mahil
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/8/e106361.full
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