MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips

In situ transmission electron microscopy with holders based on the use of micro-electromechanical systems provides valuable insights into material kinetics, yet sample preparation remains complex due to fragile silicon nitride (Si3N4) windows and the risk of leaks and contamination during dropcastin...

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Main Authors: Matthias Quintelier, Joke Hadermann
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:HardwareX
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468067225000446
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author Matthias Quintelier
Joke Hadermann
author_facet Matthias Quintelier
Joke Hadermann
author_sort Matthias Quintelier
collection DOAJ
description In situ transmission electron microscopy with holders based on the use of micro-electromechanical systems provides valuable insights into material kinetics, yet sample preparation remains complex due to fragile silicon nitride (Si3N4) windows and the risk of leaks and contamination during dropcasting. This results in failed experiments and increases experimental costs. This paper introduces the MEMS Dropcasting Tool (MDT), a cost-effective, in-house 3D-printable solution that confines the droplet to a specific area, preventing particle migration under the O-ring and reducing contamination risks at the inlet and outlet ports of closed cell chip holders.
format Article
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issn 2468-0672
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publishDate 2025-09-01
publisher Elsevier
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spelling doaj-art-cd054872a7a94098a4a9db7f77f64dbc2025-08-20T03:24:00ZengElsevierHardwareX2468-06722025-09-0123e0066610.1016/j.ohx.2025.e00666MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chipsMatthias Quintelier0Joke Hadermann1EMAT, Department of Physics, University of Antwerp 2020 Antwerp, BelgiumCorresponding author.; EMAT, Department of Physics, University of Antwerp 2020 Antwerp, BelgiumIn situ transmission electron microscopy with holders based on the use of micro-electromechanical systems provides valuable insights into material kinetics, yet sample preparation remains complex due to fragile silicon nitride (Si3N4) windows and the risk of leaks and contamination during dropcasting. This results in failed experiments and increases experimental costs. This paper introduces the MEMS Dropcasting Tool (MDT), a cost-effective, in-house 3D-printable solution that confines the droplet to a specific area, preventing particle migration under the O-ring and reducing contamination risks at the inlet and outlet ports of closed cell chip holders.http://www.sciencedirect.com/science/article/pii/S2468067225000446In situTEMSample preparationDropcasting
spellingShingle Matthias Quintelier
Joke Hadermann
MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
HardwareX
In situ
TEM
Sample preparation
Dropcasting
title MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
title_full MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
title_fullStr MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
title_full_unstemmed MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
title_short MDT: A simple tool to facilitate dropcasting on in situ TEM MEMS chips
title_sort mdt a simple tool to facilitate dropcasting on in situ tem mems chips
topic In situ
TEM
Sample preparation
Dropcasting
url http://www.sciencedirect.com/science/article/pii/S2468067225000446
work_keys_str_mv AT matthiasquintelier mdtasimpletooltofacilitatedropcastingoninsitutemmemschips
AT jokehadermann mdtasimpletooltofacilitatedropcastingoninsitutemmemschips