Review of Cathepsin K Inhibitor Development and the Potential Role of Phytochemicals
Cathepsin K plays a pivotal role in bone resorption and has emerged as a prominent therapeutic target for treating bone-related diseases such as osteoporosis. Despite significant advances in synthetic inhibitor development, none have achieved FDA approval due to safety and efficacy challenges. This...
Saved in:
| Main Author: | Dong Oh Moon |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/1/91 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sustained release of cathepsin D/cathepsin K from injectable hydrogel microspheres in anti-photoaging
by: Wenyi Hou, et al.
Published: (2025-10-01) -
THE ROLE OF CYTOKINE SYSTEM RANKL-RANK-OPG AND CATHEPSIN K IN THE PATHOGENESIS OF OSTEOPOROSIS: ACHIEVEMENTS AND PERSPECTIVES IN THE TREATMENT OF DISEASE
by: S. Sagalovsky, et al.
Published: (2015-10-01) -
Effects of the cathepsin K inhibitor with mineral trioxide aggregate cements on osteoclastic activity
by: Hee-Sun Kim, et al.
Published: (2019-05-01) -
Potency of anti-trematode in inhibiting cathepsin-2L and cathepsin-5L of Fasciola gigantica using homology, docking, and molecular dynamics
by: Henni Vanda, et al.
Published: (2024-11-01) -
The role of cathepsin S in the pathophysiology of bronchial asthma
by: A. Yu. Kraposhina, et al.
Published: (2022-10-01)