Evaluating the Efficacy and Safety of Direct Oral Anticoagulants Compared to Vitamin K Antagonists in Patients with Antiphospholipid Syndrome: Updated Systematic Review and Meta-Analysis

Evaluating the Efficacy and Safety of Direct Oral Anticoagulants Compared to Vitamin K Antagonists in Patients with Antiphospholipid Syndrome: Updated Systematic Review and Meta-Analysis

Background Antiphospholipid Syndrome (APS) is an autoimmune condition that increases thrombosis risk. Although Vitamin K antagonists (VKA) are standard treatment, interest in direct oral anticoagulants (DOAC) has grown. Recent studies evaluated DOAC across all APS subgroups. This review updates our...

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Main Authors: Lama Alfehaid PharmD, MME, Nada Alsuhebany PharmD, Hussah Albahlal PharmD, Albatoul Alomran PharmD, Abdulmajeed M Alshehri PharmD, Mohammed AlSheef MD, Abdulaali Almutairi PharmD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296251364269
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