Higher soluble thrombomodulin and angiogenic markers in continuous flow left ventricular assist device–supported patients associated with arteriovenous malformation and nonsurgical bleeding

Higher soluble thrombomodulin and angiogenic markers in continuous flow left ventricular assist device–supported patients associated with arteriovenous malformation and nonsurgical bleeding

Bleeding complications are a bane of continuous flow left ventricular assist devices (cfLVAD); gastrointestinal bleeding (GIB) from arteriovenous malformation (AVM) predominating. We hypothesized that shear stress disrupts vascular endothelium altering angiogenesis and contributing to bleeding. We p...

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Main Authors: Kavitha Muthiah, MBChB, PhD, FRACP, FCSANZ, Louise L. Dunn, BSc(Hons), PhD, Hunter Eckford, BMedSci, David Connor, BMedSci(Hons), PhD, Desiree Robson, RN, Peter S. Macdonald, MBBS, FRACP, MD, PhD, Christopher S. Hayward, MD, FRACP
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:JHLT Open
Subjects:
left ventricular assist device
mechanical circulatory support
gastrointestinal bleeding
arteriovenous malformation
angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S295013342400082X
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