A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S
The interaction of protionamide with alizarin red S (ARS) and its analytical application were carefully investigated in this contribution. The interaction conditions were carefully studied and optimized by cyclic voltammetry. Under the optimum conditions, the cyclic voltammetry curve of ARS showed a...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.1155/2015/151390 |
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| author | Weili Zhang Xueliang Niu Hua Zhang Qingqing Jiang Pingping Zhang |
| author_facet | Weili Zhang Xueliang Niu Hua Zhang Qingqing Jiang Pingping Zhang |
| author_sort | Weili Zhang |
| collection | DOAJ |
| description | The interaction of protionamide with alizarin red S (ARS) and its analytical application were carefully investigated in this contribution. The interaction conditions were carefully studied and optimized by cyclic voltammetry. Under the optimum conditions, the cyclic voltammetry curve of ARS showed an oxidation peak with the peak potential of 0.57 V. After the addition of protionamide to the ARS solution, the peak potential was negatively moved, and meanwhile the oxidation peak current decreased apparently to the concentration of protionamide and then a new method for the protionamide determination was established. The linear equation between the decreasing current (Δip) and protionamide concentration was got as Δip (μA) = 0.01514C (mg/L) −0.01553 (n=9; r=0.991) with the linear range of 10.0~50.0 mg/L, and the detection limit (3σ) was got as 8.25 μg/mL. The effects of coexisting substances on the determination were carefully investigated and the protionamide artificial and tablet samples were detected with satisfactory results. |
| format | Article |
| id | doaj-art-ccf4075889e94b5e92a88d7e42f03e15 |
| institution | Kabale University |
| issn | 2090-3529 2090-3537 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Electrochemistry |
| spelling | doaj-art-ccf4075889e94b5e92a88d7e42f03e152025-02-03T06:07:08ZengWileyInternational Journal of Electrochemistry2090-35292090-35372015-01-01201510.1155/2015/151390151390A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red SWeili Zhang0Xueliang Niu1Hua Zhang2Qingqing Jiang3Pingping Zhang4Pharmacy College, Key Laboratory of Biomedical Engineering and Technology in Universities of Shandong, Qilu Medical University, Zibo 255213, ChinaPharmacy College, Key Laboratory of Biomedical Engineering and Technology in Universities of Shandong, Qilu Medical University, Zibo 255213, ChinaPharmacy College, Key Laboratory of Biomedical Engineering and Technology in Universities of Shandong, Qilu Medical University, Zibo 255213, ChinaPharmacy College, Key Laboratory of Biomedical Engineering and Technology in Universities of Shandong, Qilu Medical University, Zibo 255213, ChinaPharmacy College, Key Laboratory of Biomedical Engineering and Technology in Universities of Shandong, Qilu Medical University, Zibo 255213, ChinaThe interaction of protionamide with alizarin red S (ARS) and its analytical application were carefully investigated in this contribution. The interaction conditions were carefully studied and optimized by cyclic voltammetry. Under the optimum conditions, the cyclic voltammetry curve of ARS showed an oxidation peak with the peak potential of 0.57 V. After the addition of protionamide to the ARS solution, the peak potential was negatively moved, and meanwhile the oxidation peak current decreased apparently to the concentration of protionamide and then a new method for the protionamide determination was established. The linear equation between the decreasing current (Δip) and protionamide concentration was got as Δip (μA) = 0.01514C (mg/L) −0.01553 (n=9; r=0.991) with the linear range of 10.0~50.0 mg/L, and the detection limit (3σ) was got as 8.25 μg/mL. The effects of coexisting substances on the determination were carefully investigated and the protionamide artificial and tablet samples were detected with satisfactory results.http://dx.doi.org/10.1155/2015/151390 |
| spellingShingle | Weili Zhang Xueliang Niu Hua Zhang Qingqing Jiang Pingping Zhang A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S International Journal of Electrochemistry |
| title | A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S |
| title_full | A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S |
| title_fullStr | A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S |
| title_full_unstemmed | A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S |
| title_short | A Novel Electrochemical Method for Protionamide Determination Based on Its Interaction with Alizarin Red S |
| title_sort | novel electrochemical method for protionamide determination based on its interaction with alizarin red s |
| url | http://dx.doi.org/10.1155/2015/151390 |
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