Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis

Abstract Background Children’s oral health significantly impacts their overall well-being, daily activities, and social interactions. Dental treatments under general anesthesia are often required for extensive dental problems, special health care needs, or dental phobias, particularly in pediatric p...

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Main Authors: Nasibe Aycan Yilmaz, Mehmet Emin Arayici, Candan Efeoglu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-025-05457-w
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author Nasibe Aycan Yilmaz
Mehmet Emin Arayici
Candan Efeoglu
author_facet Nasibe Aycan Yilmaz
Mehmet Emin Arayici
Candan Efeoglu
author_sort Nasibe Aycan Yilmaz
collection DOAJ
description Abstract Background Children’s oral health significantly impacts their overall well-being, daily activities, and social interactions. Dental treatments under general anesthesia are often required for extensive dental problems, special health care needs, or dental phobias, particularly in pediatric populations. The objective of this meta-analysis was to systematically review and synthesize existing research on how dental treatments under general anesthesia affect the oral health-related quality of life (OHRQoL) in children. Methods The electronic databases such as PubMed, EMBASE, Ovid MEDLINE, Web of Science, and Scopus were systematically reviewed following PRISMA guidelines to identify studies evaluating OHRQoL changes after dental treatments under general anesthesia. Studies involving ECOHIS and COHRQoL scales in pre- and postoperative assessments were included. The mean differences between scale measurements before and after dental treatments under general anesthesia were reported as the standard mean difference (SMD), and effect sizes for Hedges’ g were classified as follows: small effect (0.2), medium effect (0.5), large effect (0.8). All meta-analysis statistical computation was carried out using the Hartung-Knapp-Sidik-Jonkman method for the random effects model. Results A total of 36 papers satisfied the inclusion criteria and were subsequently included in the investigation. In the pooled analysis, treatments under general anesthesia in children improved OHRQoL (ECOHIS) in the short term with a significantly large effect size (SMD = 1.66, 95% CI: 1.07–2.24, p < 0.001; τ2 = 2.18, I2 = 98.9, p < 0.001). Similarly, dental treatment under general anesthesia increased the COHRQoL score in children with a significantly large effect size (SMD = 1.32, 95% CI: 0.81–1.84, p < 0.001; τ2 = 0.78, I2 = 97.3, p < 0.001). Conclusion The findings of this meta-analysis suggest that there was evidence that OHRQoL of children receiving dental treatment under general anesthesia improves with a large effect size in the short-term following treatment.
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spelling doaj-art-ccefffb3b9964075b622d9c0a79477472025-01-19T12:41:17ZengBMCBMC Oral Health1472-68312025-01-0125111510.1186/s12903-025-05457-wImpact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysisNasibe Aycan Yilmaz0Mehmet Emin Arayici1Candan Efeoglu2Department of Restorative Dentistry, Faculty of DentistryDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Dokuz Eylül UniversityDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dokuz Eylül UniversityAbstract Background Children’s oral health significantly impacts their overall well-being, daily activities, and social interactions. Dental treatments under general anesthesia are often required for extensive dental problems, special health care needs, or dental phobias, particularly in pediatric populations. The objective of this meta-analysis was to systematically review and synthesize existing research on how dental treatments under general anesthesia affect the oral health-related quality of life (OHRQoL) in children. Methods The electronic databases such as PubMed, EMBASE, Ovid MEDLINE, Web of Science, and Scopus were systematically reviewed following PRISMA guidelines to identify studies evaluating OHRQoL changes after dental treatments under general anesthesia. Studies involving ECOHIS and COHRQoL scales in pre- and postoperative assessments were included. The mean differences between scale measurements before and after dental treatments under general anesthesia were reported as the standard mean difference (SMD), and effect sizes for Hedges’ g were classified as follows: small effect (0.2), medium effect (0.5), large effect (0.8). All meta-analysis statistical computation was carried out using the Hartung-Knapp-Sidik-Jonkman method for the random effects model. Results A total of 36 papers satisfied the inclusion criteria and were subsequently included in the investigation. In the pooled analysis, treatments under general anesthesia in children improved OHRQoL (ECOHIS) in the short term with a significantly large effect size (SMD = 1.66, 95% CI: 1.07–2.24, p < 0.001; τ2 = 2.18, I2 = 98.9, p < 0.001). Similarly, dental treatment under general anesthesia increased the COHRQoL score in children with a significantly large effect size (SMD = 1.32, 95% CI: 0.81–1.84, p < 0.001; τ2 = 0.78, I2 = 97.3, p < 0.001). Conclusion The findings of this meta-analysis suggest that there was evidence that OHRQoL of children receiving dental treatment under general anesthesia improves with a large effect size in the short-term following treatment.https://doi.org/10.1186/s12903-025-05457-wQuality of lifeChildrenDental treatmentMeta-analysis
spellingShingle Nasibe Aycan Yilmaz
Mehmet Emin Arayici
Candan Efeoglu
Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
BMC Oral Health
Quality of life
Children
Dental treatment
Meta-analysis
title Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
title_full Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
title_fullStr Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
title_full_unstemmed Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
title_short Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis
title_sort impact of dental treatments under general anesthesia on oral health related quality of life in children a comprehensive meta analysis
topic Quality of life
Children
Dental treatment
Meta-analysis
url https://doi.org/10.1186/s12903-025-05457-w
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AT mehmeteminarayici impactofdentaltreatmentsundergeneralanesthesiaonoralhealthrelatedqualityoflifeinchildrenacomprehensivemetaanalysis
AT candanefeoglu impactofdentaltreatmentsundergeneralanesthesiaonoralhealthrelatedqualityoflifeinchildrenacomprehensivemetaanalysis