An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)

<p>Sweet and bitter taste on cassava tuber is affected by starch metabolisms. Meisa1 gene is a gene in cassava (Manihot esculenta Crantz.) encoding isoamylase1 enzyme involved in starch metabolisms. This study aimed to analyze partial DNA sequences of Meisa1 gene on sweet and bitter cassavas c...

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Main Authors: Dewi Indriyani Roslim, Fitriyatun Nisa, Herman Herman
Format: Article
Language:English
Published: Universitas Negeri Semarang 2016-04-01
Series:Biosaintifika: Journal of Biology & Biology Education
Subjects:
Online Access:https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/5365
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author Dewi Indriyani Roslim
Fitriyatun Nisa
Herman Herman
author_facet Dewi Indriyani Roslim
Fitriyatun Nisa
Herman Herman
author_sort Dewi Indriyani Roslim
collection DOAJ
description <p>Sweet and bitter taste on cassava tuber is affected by starch metabolisms. Meisa1 gene is a gene in cassava (Manihot esculenta Crantz.) encoding isoamylase1 enzyme involved in starch metabolisms. This study aimed to analyze partial DNA sequences of Meisa1 gene on sweet and bitter cassavas collected by Genetics Laboratory, Department Biology, Faculty of Mathematics and Natural Sciences, Riau University, Indonesia. Methods included total DNA extraction from fresh young leaves of cassava using CTAB buffer, polymerase chain reaction (PCR), electrophoresis, and sequencing. The obtained data were analyzed using MEGA software version 5. The results showed that there were nucleotide variations in the intron region, not in the exon region. The variations were caused by the transition substitution mutation (35.39%) and transversion substitution mutation (64.61%). The genetic distance range between seven cassava genotypes was approximately 0% to 11%. Partial DNA sequence variations of Meisa1 gene located in intron region were unable to cluster seven cassava genotypes separately into two groups based on tuber taste.</p><p><strong>How to Cite</strong></p><p>Roslim, D., Nisa, F., &amp; Herman, H. (2016). An Analysis of Partial DNA Sequence of <em>Meisa1</em> Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.). <em>Biosaintifika: Journal of Biology &amp; Biology Education</em>, 8(1) 103-110.</p>
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issn 2085-191X
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spelling doaj-art-cceb1e8e38e54c8ead5da412a9dc99cd2025-08-20T02:02:45ZengUniversitas Negeri SemarangBiosaintifika: Journal of Biology & Biology Education2085-191X2338-76102016-04-018110511210.15294/biosaintifika.v8i1.53654266An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)Dewi Indriyani Roslim0Fitriyatun Nisa1Herman Herman2Department of Biology, Faculty of Mathematics and Natural Science, Universitas Riau, Indonesia, Kampus Bina Widya, Jl. HR Soebrantas, Panam, Pekanbaru 28293, RiauDepartment of Biology, Faculty of Mathematics and Natural Science, Universitas Riau, Indonesia, Kampus Bina Widya, Jl. HR Soebrantas, Panam, Pekanbaru 28293, RiauDepartment of Biology, Faculty of Mathematics and Natural Science, Universitas Riau, Indonesia, Kampus Bina Widya, Jl. HR Soebrantas, Panam, Pekanbaru 28293, Riau<p>Sweet and bitter taste on cassava tuber is affected by starch metabolisms. Meisa1 gene is a gene in cassava (Manihot esculenta Crantz.) encoding isoamylase1 enzyme involved in starch metabolisms. This study aimed to analyze partial DNA sequences of Meisa1 gene on sweet and bitter cassavas collected by Genetics Laboratory, Department Biology, Faculty of Mathematics and Natural Sciences, Riau University, Indonesia. Methods included total DNA extraction from fresh young leaves of cassava using CTAB buffer, polymerase chain reaction (PCR), electrophoresis, and sequencing. The obtained data were analyzed using MEGA software version 5. The results showed that there were nucleotide variations in the intron region, not in the exon region. The variations were caused by the transition substitution mutation (35.39%) and transversion substitution mutation (64.61%). The genetic distance range between seven cassava genotypes was approximately 0% to 11%. Partial DNA sequence variations of Meisa1 gene located in intron region were unable to cluster seven cassava genotypes separately into two groups based on tuber taste.</p><p><strong>How to Cite</strong></p><p>Roslim, D., Nisa, F., &amp; Herman, H. (2016). An Analysis of Partial DNA Sequence of <em>Meisa1</em> Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.). <em>Biosaintifika: Journal of Biology &amp; Biology Education</em>, 8(1) 103-110.</p>https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/5365DNA sequenceManihot esculenta CrantzMeisa1 genemutationPCR
spellingShingle Dewi Indriyani Roslim
Fitriyatun Nisa
Herman Herman
An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
Biosaintifika: Journal of Biology & Biology Education
DNA sequence
Manihot esculenta Crantz
Meisa1 gene
mutation
PCR
title An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
title_full An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
title_fullStr An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
title_full_unstemmed An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
title_short An Analysis of Partial DNA Sequence of Meisa1 Gene on Sweet and Bitter Cassavas (Manihot esculenta Crantz.)
title_sort analysis of partial dna sequence of meisa1 gene on sweet and bitter cassavas manihot esculenta crantz
topic DNA sequence
Manihot esculenta Crantz
Meisa1 gene
mutation
PCR
url https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/5365
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