Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment

<b>Background/Objectives:</b> Data about metabolic syndrome (MS) in people who use drugs (PWUD) undergoing treatment for recovery are limited. We aimed to explore the extent of the MS and its predominant components and determinants in a sample of PWUD undergoing treatment for recovery th...

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Main Authors: Nadine Mahboub, Elissa Ayoub, Carine Mounzer, Tatiana Kate Baltagi, Dimitrios Papandreou, Nanne de Vries, Rana Rizk
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Clinics and Practice
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Online Access:https://www.mdpi.com/2039-7283/14/6/210
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author Nadine Mahboub
Elissa Ayoub
Carine Mounzer
Tatiana Kate Baltagi
Dimitrios Papandreou
Nanne de Vries
Rana Rizk
author_facet Nadine Mahboub
Elissa Ayoub
Carine Mounzer
Tatiana Kate Baltagi
Dimitrios Papandreou
Nanne de Vries
Rana Rizk
author_sort Nadine Mahboub
collection DOAJ
description <b>Background/Objectives:</b> Data about metabolic syndrome (MS) in people who use drugs (PWUD) undergoing treatment for recovery are limited. We aimed to explore the extent of the MS and its predominant components and determinants in a sample of PWUD undergoing treatment for recovery through rehabilitation or opioid substitution treatment (OST) in Lebanon. Furthermore, we investigated the effect of each treatment modality on the MS; <b>Methods:</b> This was a cross-sectional study, in which demographics and treatment-related, nutritional, and biochemical data of the participants were collected. MS was defined according to the American Heart Association and the National Heart, Lung, and Blood Institute (AHA/NHLBI) criteria. Descriptive statistics were presented, and bivariate and multivariate analyses were conducted; <b>Results:</b> A total of 155 male subjects with the following characteristics were included: OST: n = 80; rehabilitation: n = 75; mean age: 32.53 ± 8.39 years; mean body mass index (BMI): 27.41 ± 4.99 Kg/m<sup>2</sup>; mean duration of treatment: 18 months. More than half of the sample had low HDL-C (56.8%) and/or elevated blood pressure (51.6%), 42.9% had elevated WC, 21.9% had elevated TG, and 12.3% had elevated FBS. Furthermore, 7.2% of the sample had no components of the MS, 29.2% had one component, 40.9% had two components, 16.9% had three components, and 5.8% had four components. MS was identified in 22.7% of the sample. Higher age was associated with higher odds of being diagnosed with MS (OR = 1.072; 95% CI: 1.021–1.126), whereas higher duration of current treatment was associated with lower odds (OR = 0.969; 95% CI: 0.944–0.995); <b>Conclusions:</b> MS and its components are prevalent in PWUD undergoing treatment for recovery. Routine screening and preventive measures are essential to prevent metabolic syndrome, particularly among older people and treatment newcomers.
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spelling doaj-art-cce903960cf5455485f74006f8132e412025-08-20T02:00:35ZengMDPI AGClinics and Practice2039-72832024-12-011462661268010.3390/clinpract14060210Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution TreatmentNadine Mahboub0Elissa Ayoub1Carine Mounzer2Tatiana Kate Baltagi3Dimitrios Papandreou4Nanne de Vries5Rana Rizk6Department of Nutrition and Food Sciences, Faculty of Arts and Sciences, Lebanese International University, Beirut P.O. Box 146404, LebanonDepartment of Nutrition and Dietetics, Faculty of Public Health Branch 2, Lebanese University, Beirut P.O. Box 6573, LebanonDepartment of Nutrition and Dietetics, Faculty of Public Health Branch 2, Lebanese University, Beirut P.O. Box 6573, LebanonDepartment of Biochemistry, College of Arts and Sciences, Case Western Reserve University, Cleveland, OH 44106, USADepartment of Clinical Nutrition & Dietetics, College of Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab EmiratesDepartment of Health Promotion, CAPHRI School for Public Health and Primary Care, Maastricht University, P.O. Box 616, 6200 LK Maastricht, The NetherlandsDepartment of Nutrition and Food Science, Faculty of Arts and Sciences, Lebanese American University, Byblos P.O. Box 36, Lebanon<b>Background/Objectives:</b> Data about metabolic syndrome (MS) in people who use drugs (PWUD) undergoing treatment for recovery are limited. We aimed to explore the extent of the MS and its predominant components and determinants in a sample of PWUD undergoing treatment for recovery through rehabilitation or opioid substitution treatment (OST) in Lebanon. Furthermore, we investigated the effect of each treatment modality on the MS; <b>Methods:</b> This was a cross-sectional study, in which demographics and treatment-related, nutritional, and biochemical data of the participants were collected. MS was defined according to the American Heart Association and the National Heart, Lung, and Blood Institute (AHA/NHLBI) criteria. Descriptive statistics were presented, and bivariate and multivariate analyses were conducted; <b>Results:</b> A total of 155 male subjects with the following characteristics were included: OST: n = 80; rehabilitation: n = 75; mean age: 32.53 ± 8.39 years; mean body mass index (BMI): 27.41 ± 4.99 Kg/m<sup>2</sup>; mean duration of treatment: 18 months. More than half of the sample had low HDL-C (56.8%) and/or elevated blood pressure (51.6%), 42.9% had elevated WC, 21.9% had elevated TG, and 12.3% had elevated FBS. Furthermore, 7.2% of the sample had no components of the MS, 29.2% had one component, 40.9% had two components, 16.9% had three components, and 5.8% had four components. MS was identified in 22.7% of the sample. Higher age was associated with higher odds of being diagnosed with MS (OR = 1.072; 95% CI: 1.021–1.126), whereas higher duration of current treatment was associated with lower odds (OR = 0.969; 95% CI: 0.944–0.995); <b>Conclusions:</b> MS and its components are prevalent in PWUD undergoing treatment for recovery. Routine screening and preventive measures are essential to prevent metabolic syndrome, particularly among older people and treatment newcomers.https://www.mdpi.com/2039-7283/14/6/210substance use disordermetabolic syndromerehabilitationopioid substitution treatmentLebanon
spellingShingle Nadine Mahboub
Elissa Ayoub
Carine Mounzer
Tatiana Kate Baltagi
Dimitrios Papandreou
Nanne de Vries
Rana Rizk
Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
Clinics and Practice
substance use disorder
metabolic syndrome
rehabilitation
opioid substitution treatment
Lebanon
title Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
title_full Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
title_fullStr Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
title_full_unstemmed Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
title_short Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment
title_sort metabolic syndrome as a risk factor among lebanese patients with substance use disorder undergoing treatment for recovery through rehabilitation or opioid substitution treatment
topic substance use disorder
metabolic syndrome
rehabilitation
opioid substitution treatment
Lebanon
url https://www.mdpi.com/2039-7283/14/6/210
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