Integrative Mendelian Randomization and Transcriptome Analysis Unveil Dual Pathways in Prostate Cancer Etiology
Conclusion: The study highlighted a significant association between prostate cancer occurrence, glutathione metabolism, and monocyte activity. The critical interplay between glutathione metabolism and immune cell dynamics in prostate cancer is underscored, proposing novel biomarkers for early diagno...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/ijcp/9943789 |
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| Summary: | Conclusion: The study highlighted a significant association between prostate cancer occurrence, glutathione metabolism, and monocyte activity. The critical interplay between glutathione metabolism and immune cell dynamics in prostate cancer is underscored, proposing novel biomarkers for early diagnosis and potential therapeutic targets. Notably, ATP6V1G1 emerged as a key gene with significant diagnostic and prognostic value, offering new prospects for therapeutic intervention in prostate cancer. |
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| ISSN: | 1742-1241 |