Targeting tumor-associated macrophages in gastric cancer progression and therapy: insights from molecular mechanisms to therapeutic applications

Targeting tumor-associated macrophages in gastric cancer progression and therapy: insights from molecular mechanisms to therapeutic applications

Gastric cancer (GC) is the fifth most common malignant tumor that imposes heavily public health burdens worldwide. Systemic therapies for gastric cancer (GC), such as chemotherapy, targeted therapy, and immunotherapy, have undergone significant advancements. Nevertheless, the extensive application o...

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Bibliographic Details
Main Authors: ChengTao Wan, Jie Deng, Yu Zhu, Li Wan, Linyue Xu, Qiuyan Chen, Can Zou, Ju Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
tumor-associated macrophage
tumor microenvironment
tumor progression
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1549694/full
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