10 kHz spinal cord stimulation vs. traditional low-frequency spinal cord stimulation for the treatment of diabetes peripheral neuropathic pain: study protocol for a multi-center randomized controlled clinical trial

10 kHz spinal cord stimulation vs. traditional low-frequency spinal cord stimulation for the treatment of diabetes peripheral neuropathic pain: study protocol for a multi-center randomized controlled clinical trial

BackgroundDiabetic peripheral neuropathic pain (DPNP), affecting ~50% of diabetes patients, imposes major burdens on quality of life and healthcare systems, while current therapies including pharmacotherapy and conventional spinal cord stimulation remain limited by insufficient efficacy and adverse...

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Bibliographic Details
Main Authors: Chen Li, Chun-Hua Liu, Yi-Fan Li, Hui-Min Hu, Qing Shi, An-Xiang Liu, Wen-Hui Liu, Yi Zhang, Peng Mao, Bi-Fa Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neurology
Subjects:
diabetic peripheral neuropathic pain
high-frequency spinal cord stimulation
randomized controlled trial
neuromodulation
protocol
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1611970/full
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