Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-181c-5p Promote BMP2-Induced Repair of Cartilage Injury through Inhibition of SMAD7 Expression
The therapy role of mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) in cartilage regeneration has been well studied. Herein, we tried to analyze the role of human umbilical cord MSC- (hUCMSC-) EVs carrying microRNA- (miR-) 181c-5p in repair of cartilage injury. After successful is...
Saved in:
| Main Authors: | Qiang Zhang, Le Cao, Shanqi Zou, Yuanling Feng, Xudong Miao, Lu Huang, Yongping Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2022/1157498 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation
by: Zeji Du, et al.
Published: (2025-06-01) -
Synergistic effect of umbilical cord extracellular vesicles and rhBMP-2 to enhance the regeneration of a metaphyseal femoral defect in osteoporotic rats
by: Amelie Deluca, et al.
Published: (2024-05-01) -
First‐In‐Human Application of Human Umbilical Cord‐Derived Extracellular Vesicles in Tethered Spinal Cord Release Surgery
by: Matthias Krause, et al.
Published: (2025-06-01) -
Mesenchymal stem cells and their extracellular vesicles: new therapies for cartilage repair
by: Hongwei Yang, et al.
Published: (2025-04-01) -
Effects of Extracellular Vesicles Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells on Cell Immunity in Nonobese Mice
by: Yang Ou, et al.
Published: (2024-01-01)