Predictive metabolite signatures for risk of progression to active TB from QuantiFERON supernatants of household contacts of TB patients

Predictive metabolite signatures for risk of progression to active TB from QuantiFERON supernatants of household contacts of TB patients

The identification of individuals with the greatest risk of progression to active tuberculosis (TB) disease from the huge reservoir of Mycobacterium tuberculosis (Mtb) infected individuals continues to remain an arduous ascent in the global effort to control TB. In a two-year prospective study, we a...

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Main Authors: Evangeline Ann Daniel, Shubham Upadhyay, Murugesan Selvachithiram, Sathyamurthi Pattabiraman, Brindha Bhanu, Amsaveni Sivaprakasam, Vandana Kulkarni, Rajesh Karyakarte, Sanjay Gaikwad, Mandar Paradkar, Shri Vijay Bala Yogendra Shivakumar, Vidya Mave, Amita Gupta, Keshava Prasad, Luke Elizabeth Hanna
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Metabolites
tuberculosis
progression
QuantiFERON supernatant
biomarkers
metabolite signatures
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2437242
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