Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis
The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher fanti value than males. Younger participants exhibited had higher serum DPs concentrations and fanti values compared to ol...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325007468 |
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| author | Ye Wu Yuhao Fan Xinyu Lou Dan Chen Jun jin Ying Wang Ting Yang Zhiyan Liu |
| author_facet | Ye Wu Yuhao Fan Xinyu Lou Dan Chen Jun jin Ying Wang Ting Yang Zhiyan Liu |
| author_sort | Ye Wu |
| collection | DOAJ |
| description | The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher fanti value than males. Younger participants exhibited had higher serum DPs concentrations and fanti values compared to older age groups, compared to middle-aged and elderly groups, indicating a tendency for anti-DP accumulation. In addition, the fanti value was found to be lower in patients with metastatic thyroid tumor, potentially due to an enhanced capacity to metabolize anti-DP post-metastasis. We also examined the population of patients with varying diameters. Consequently, future studies should further investigate the possible relationship between DPs and thyroid function, with an emphasis on anti-DP. |
| format | Article |
| id | doaj-art-ccd4241eceb24ab096a42f88dfd43ebc |
| institution | DOAJ |
| issn | 0147-6513 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj-art-ccd4241eceb24ab096a42f88dfd43ebc2025-08-20T03:07:50ZengElsevierEcotoxicology and Environmental Safety0147-65132025-07-0129911841010.1016/j.ecoenv.2025.118410Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasisYe Wu0Yuhao Fan1Xinyu Lou2Dan Chen3Jun jin4Ying Wang5Ting Yang6Zhiyan Liu7College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China; Cosco Shipping (Guangzhou) Co.,Ltd., Guangzhou, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China; Engineering Research Center of Food Environment and Public Health, Beijing 100081, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China; Engineering Research Center of Food Environment and Public Health, Beijing 100081, ChinaCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, China; Corresponding authors.Department of Pathology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China; Corresponding authors.The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher fanti value than males. Younger participants exhibited had higher serum DPs concentrations and fanti values compared to older age groups, compared to middle-aged and elderly groups, indicating a tendency for anti-DP accumulation. In addition, the fanti value was found to be lower in patients with metastatic thyroid tumor, potentially due to an enhanced capacity to metabolize anti-DP post-metastasis. We also examined the population of patients with varying diameters. Consequently, future studies should further investigate the possible relationship between DPs and thyroid function, with an emphasis on anti-DP.http://www.sciencedirect.com/science/article/pii/S0147651325007468Dechlorane PlusThyroidSerum concentrationMolecular docking |
| spellingShingle | Ye Wu Yuhao Fan Xinyu Lou Dan Chen Jun jin Ying Wang Ting Yang Zhiyan Liu Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis Ecotoxicology and Environmental Safety Dechlorane Plus Thyroid Serum concentration Molecular docking |
| title | Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis |
| title_full | Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis |
| title_fullStr | Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis |
| title_full_unstemmed | Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis |
| title_short | Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis |
| title_sort | serum dechlorane plus dps levels in thyroid disease patients influence of gender age and metastasis |
| topic | Dechlorane Plus Thyroid Serum concentration Molecular docking |
| url | http://www.sciencedirect.com/science/article/pii/S0147651325007468 |
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