The Role of Symmetric Stem Cell Divisions in Tissue Homeostasis.

Successful maintenance of cellular lineages critically depends on the fate decision dynamics of stem cells (SCs) upon division. There are three possible strategies with respect to SC fate decision symmetry: (a) asymmetric mode, when each and every SC division produces one SC and one non-SC progeny;...

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Bibliographic Details
Main Authors: Jienian Yang, Maksim V Plikus, Natalia L Komarova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004629&type=printable
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