An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis

Many cases of atopic myelitis have been reported in Japan; however very few were described in western countries. An 82-year-old woman with a past medical history of atopic dermatitis and asthma presented with progressive paresthesia (tingling) of both hands and tetraparesis. Before the onset of neur...

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Main Authors: Alev Leventoglu, Pelin Ozlu, Ferda Ince
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/489451
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author Alev Leventoglu
Pelin Ozlu
Ferda Ince
author_facet Alev Leventoglu
Pelin Ozlu
Ferda Ince
author_sort Alev Leventoglu
collection DOAJ
description Many cases of atopic myelitis have been reported in Japan; however very few were described in western countries. An 82-year-old woman with a past medical history of atopic dermatitis and asthma presented with progressive paresthesia (tingling) of both hands and tetraparesis. Before the onset of neurological symptoms, she complained of ichthyosis of both legs for 5 weeks. Magnetic resonance imaging demonstrated multisegmental degenerative arthritis, degenerative disc disease, and abnormal spinal cord signal intensity over several cervical segments, suggesting the diagnosis of myelitis. Total serum IgE level was elevated. Nerve conduction studies revealed asymmetric axonal sensorimotor neuropathy. The cerebrospinal fluid specimen showed lymphocytic pleocytosis and elevated protein level. Based on clinical, imaging, and laboratory findings, atopic myelitis was diagnosed. The diagnosis of atopic myelitis should be considered in myelopathy patients with history of atopy and elevated serum IgE levels.
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spelling doaj-art-ccc43968ffcb402caaaabcb41846fd5f2025-08-20T03:19:31ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/489451489451An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic MyelitisAlev Leventoglu0Pelin Ozlu1Ferda Ince2Department of Neurology, Ufuk University Medical School, Ankara, TurkeyDepartment of Neurology, Ufuk University Medical School, Ankara, TurkeyDepartment of Neurology, Ufuk University Medical School, Ankara, TurkeyMany cases of atopic myelitis have been reported in Japan; however very few were described in western countries. An 82-year-old woman with a past medical history of atopic dermatitis and asthma presented with progressive paresthesia (tingling) of both hands and tetraparesis. Before the onset of neurological symptoms, she complained of ichthyosis of both legs for 5 weeks. Magnetic resonance imaging demonstrated multisegmental degenerative arthritis, degenerative disc disease, and abnormal spinal cord signal intensity over several cervical segments, suggesting the diagnosis of myelitis. Total serum IgE level was elevated. Nerve conduction studies revealed asymmetric axonal sensorimotor neuropathy. The cerebrospinal fluid specimen showed lymphocytic pleocytosis and elevated protein level. Based on clinical, imaging, and laboratory findings, atopic myelitis was diagnosed. The diagnosis of atopic myelitis should be considered in myelopathy patients with history of atopy and elevated serum IgE levels.http://dx.doi.org/10.1155/2013/489451
spellingShingle Alev Leventoglu
Pelin Ozlu
Ferda Ince
An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
Case Reports in Neurological Medicine
title An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
title_full An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
title_fullStr An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
title_full_unstemmed An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
title_short An Unusual Case of Subclinical Peripheral Neuropathy and Cervical Spondylosis in Atopic Myelitis
title_sort unusual case of subclinical peripheral neuropathy and cervical spondylosis in atopic myelitis
url http://dx.doi.org/10.1155/2013/489451
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