PDP1 related ferroptosis risk signature indicates distinct immune microenvironment and prognosis of breast cancer patients

PDP1 related ferroptosis risk signature indicates distinct immune microenvironment and prognosis of breast cancer patients

ObjectiveWe aim to construct a RiskScore model to aid in the early prognosis of breast cancer (BC).MethodsBC mRNA expression profiles were obtained from TCGA and GEO databases. Differential gene expression analysis identifies PDP1-ferroptosis-related genes. LASSO Cox regression was utilized to scree...

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Bibliographic Details
Main Authors:	Yufeng Wang, Huifen Dang, Gongjian Zhu, Yingxia Tian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Pharmacology
Subjects:	breast cancer LASSO-cox regression analysis prognosis PDP1 ACSL1 BNIP3
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1551325/full
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