The utility of neuro-QOL in idiopathic REM sleep behavior disorder
Abstract Introduction Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) can affect quality of life (QOL) for both patient and bed partner; has been less well-studied. Utilizing the Neuro-QOL, we aimed to investigate QOL complaints in subjects with iRBD, and whether QOL changes were...
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| Language: | English |
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BMC
2024-12-01
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| Series: | Sleep Science and Practice |
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| Online Access: | https://doi.org/10.1186/s41606-024-00116-5 |
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| author | Daniel A. Barone Harini Sarva Natalie Hellmers Fei Wang Zhenxing Xu Ana C. Krieger Claire Henchcliffe |
| author_facet | Daniel A. Barone Harini Sarva Natalie Hellmers Fei Wang Zhenxing Xu Ana C. Krieger Claire Henchcliffe |
| author_sort | Daniel A. Barone |
| collection | DOAJ |
| description | Abstract Introduction Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) can affect quality of life (QOL) for both patient and bed partner; has been less well-studied. Utilizing the Neuro-QOL, we aimed to investigate QOL complaints in subjects with iRBD, and whether QOL changes were associated with phenoconversion to neurodegenerative illness. Methods We prospectively enrolled subjects from the “REM Sleep Behavior Disorder Associations with Parkinson’s Disease Study (RAPiDS)” cohort and evaluated them via the NeuroQOL, both at baseline and then at follow-up evaluations. Determination of phenoconversion was ascertained from physical examination and medical chart review. Results Of those who completed both evaluations, there were 33 subjects with iRBD, with an average age of 61.9 ± 13.0 years, with 13 women and 26 men. Various QOL changes were found among those who phenoconverted versus those who did not; but following correction, none of these changes were significant. Conclusions This is the first time the Neuro-QOL has been studied in iRBD. QOL can be affected in this condition, but other screening tools will likely be needed for future studies. |
| format | Article |
| id | doaj-art-ccbb1a4d7fcd42009608fcf81880189e |
| institution | OA Journals |
| issn | 2398-2683 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Sleep Science and Practice |
| spelling | doaj-art-ccbb1a4d7fcd42009608fcf81880189e2025-08-20T02:37:54ZengBMCSleep Science and Practice2398-26832024-12-01811610.1186/s41606-024-00116-5The utility of neuro-QOL in idiopathic REM sleep behavior disorderDaniel A. Barone0Harini Sarva1Natalie Hellmers2Fei Wang3Zhenxing Xu4Ana C. Krieger5Claire Henchcliffe6Weill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineUniversity of California, Irvine, School of MedicineAbstract Introduction Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) can affect quality of life (QOL) for both patient and bed partner; has been less well-studied. Utilizing the Neuro-QOL, we aimed to investigate QOL complaints in subjects with iRBD, and whether QOL changes were associated with phenoconversion to neurodegenerative illness. Methods We prospectively enrolled subjects from the “REM Sleep Behavior Disorder Associations with Parkinson’s Disease Study (RAPiDS)” cohort and evaluated them via the NeuroQOL, both at baseline and then at follow-up evaluations. Determination of phenoconversion was ascertained from physical examination and medical chart review. Results Of those who completed both evaluations, there were 33 subjects with iRBD, with an average age of 61.9 ± 13.0 years, with 13 women and 26 men. Various QOL changes were found among those who phenoconverted versus those who did not; but following correction, none of these changes were significant. Conclusions This is the first time the Neuro-QOL has been studied in iRBD. QOL can be affected in this condition, but other screening tools will likely be needed for future studies.https://doi.org/10.1186/s41606-024-00116-5RBDParkinsonismParkinsonNeurodegenerationQuality of lifePhenoconversion |
| spellingShingle | Daniel A. Barone Harini Sarva Natalie Hellmers Fei Wang Zhenxing Xu Ana C. Krieger Claire Henchcliffe The utility of neuro-QOL in idiopathic REM sleep behavior disorder Sleep Science and Practice RBD Parkinsonism Parkinson Neurodegeneration Quality of life Phenoconversion |
| title | The utility of neuro-QOL in idiopathic REM sleep behavior disorder |
| title_full | The utility of neuro-QOL in idiopathic REM sleep behavior disorder |
| title_fullStr | The utility of neuro-QOL in idiopathic REM sleep behavior disorder |
| title_full_unstemmed | The utility of neuro-QOL in idiopathic REM sleep behavior disorder |
| title_short | The utility of neuro-QOL in idiopathic REM sleep behavior disorder |
| title_sort | utility of neuro qol in idiopathic rem sleep behavior disorder |
| topic | RBD Parkinsonism Parkinson Neurodegeneration Quality of life Phenoconversion |
| url | https://doi.org/10.1186/s41606-024-00116-5 |
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