Hybrid Immunity Overcomes Defective Immune Response to COVID-19 Vaccination in Kidney Transplant Recipients

Hybrid Immunity Overcomes Defective Immune Response to COVID-19 Vaccination in Kidney Transplant Recipients

Introduction: Comorbidities and immunosuppressive therapies are associated with reduced immune responses to primary COVID-19 mRNA vaccination in kidney transplant recipients (KTRs). In healthy individuals, prior SARS-COV-2 infection is associated with increased vaccine responses, a phenotype called...

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Main Authors: Nicolas Gemander, Delphine Kemlin, Stéphanie Depickère, Natasha S. Kelkar, Pieter Pannus, Shilpee Sharma, Alexandra Waegemans, Véronique Olislagers, Daphnée Georges, Emilie Dhondt, Margarida Braga, Leo Heyndrickx, Johan Michiels, Anaïs Thiriard, Anne Lemy, Marylène Vandevenne, Maria E. Goossens, André Matagne, Isabelle Desombere, Kevin K. Ariën, Margaret E. Ackerman, Alain Le Moine, Arnaud Marchant
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Kidney International Reports
Subjects:
COVID-19
hybrid immunity
kidney transplantation
mRNA vaccination
nonneutralizing antibodies
systems immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024923016303
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