The gene expression of caspase 3, matrix metalloproteinase-9, tissue inhibitor of metalloproteinases-1, and cathepsins S and K in patients with osteoarthritis requiring large joint replacement

Osteoarthritis (OA) is a chronic rheumatic disease that is characterized by pain and articular cartilage degradation. Pain in OA is a main clinical symptom that limits working capacity and is one of the indications for joint replacement. However, 10-40% of patients with OA also continue to experienc...

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Bibliographic Details
Main Authors: E. V. Chetina, K. E. Glemba, G. A. Markova, S. A. Makarov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-05-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/1016
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