Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana.

Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana.

A challenge in studying diverse multi-copy gene families is deciphering distinct functional types within immense sequence variation. Functional changes can in some cases be tracked through the evolutionary history of a gene family; however phylogenetic approaches are not possible in cases where gene...

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Bibliographic Details
Main Authors: Mary M Rorick, Edward B Baskerville, Thomas S Rask, Karen P Day, Mercedes Pascual
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Computational Biology
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pcbi.1006174/2/pcbi.1006174.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210219%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210219T065324Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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