Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study

Introduction: Venous thromboembolism (VTE) is a rare but potentially serious complication following anterior cruciate ligament reconstruction (ACLR). There is no guideline for the routine use of anticoagulants post-ACLR surgery. Methods: This retrospective case-control study reviewed 199 patients wh...

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Main Authors: Afana Hatem B., Ashokan Shine, Nau Thomas
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:SICOT-J
Subjects:
Online Access:https://www.sicot-j.org/articles/sicotj/full_html/2025/01/sicotj250049/sicotj250049.html
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author Afana Hatem B.
Ashokan Shine
Nau Thomas
author_facet Afana Hatem B.
Ashokan Shine
Nau Thomas
author_sort Afana Hatem B.
collection DOAJ
description Introduction: Venous thromboembolism (VTE) is a rare but potentially serious complication following anterior cruciate ligament reconstruction (ACLR). There is no guideline for the routine use of anticoagulants post-ACLR surgery. Methods: This retrospective case-control study reviewed 199 patients who underwent ACLR between February 2020 and November 2024. Two groups were compared: Group A (n = 113) received no pharmacological prophylaxis, while Group B (n = 86) received low-molecular-weight heparin (LMWH) for 2 weeks postoperatively. The incidence of symptomatic VTE, postoperative bleeding, and related complications was evaluated. Results: No symptomatic VTE or bleeding complications were observed in either group. There was no statistically significant difference between the groups in terms of age, BMI, smoking, comorbidities, and postoperative weight bearing. There was a significant difference in surgical duration, graft type, and meniscal procedure. Discussion: Our findings support a risk-stratified approach rather than universal pharmacologic prophylaxis in ACLR patients.
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spelling doaj-art-cc85ceea14074e10b486d3a3779847ec2025-08-20T03:12:38ZengEDP SciencesSICOT-J2426-88872025-01-01113810.1051/sicotj/2025032sicotj250049Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control studyAfana Hatem B.0https://orcid.org/0000-0003-3367-141XAshokan Shine1https://orcid.org/0009-0006-2298-2481Nau Thomas2https://orcid.org/0000-0003-4654-2991Orthopaedic Department, King’s College Hospital London DubaiOrthopaedic Department, King’s College Hospital London DubaiOrthopaedic Department, King’s College Hospital London DubaiIntroduction: Venous thromboembolism (VTE) is a rare but potentially serious complication following anterior cruciate ligament reconstruction (ACLR). There is no guideline for the routine use of anticoagulants post-ACLR surgery. Methods: This retrospective case-control study reviewed 199 patients who underwent ACLR between February 2020 and November 2024. Two groups were compared: Group A (n = 113) received no pharmacological prophylaxis, while Group B (n = 86) received low-molecular-weight heparin (LMWH) for 2 weeks postoperatively. The incidence of symptomatic VTE, postoperative bleeding, and related complications was evaluated. Results: No symptomatic VTE or bleeding complications were observed in either group. There was no statistically significant difference between the groups in terms of age, BMI, smoking, comorbidities, and postoperative weight bearing. There was a significant difference in surgical duration, graft type, and meniscal procedure. Discussion: Our findings support a risk-stratified approach rather than universal pharmacologic prophylaxis in ACLR patients.https://www.sicot-j.org/articles/sicotj/full_html/2025/01/sicotj250049/sicotj250049.htmlacl reconstructionthromboprophylaxisdeep vein thrombosisvenous thromboembolism
spellingShingle Afana Hatem B.
Ashokan Shine
Nau Thomas
Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
SICOT-J
acl reconstruction
thromboprophylaxis
deep vein thrombosis
venous thromboembolism
title Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
title_full Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
title_fullStr Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
title_full_unstemmed Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
title_short Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study
title_sort venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction retrospective case control study
topic acl reconstruction
thromboprophylaxis
deep vein thrombosis
venous thromboembolism
url https://www.sicot-j.org/articles/sicotj/full_html/2025/01/sicotj250049/sicotj250049.html
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AT ashokanshine venousthromboembolismprophylaxisafteranteriorcruciateligamentreconstructionretrospectivecasecontrolstudy
AT nauthomas venousthromboembolismprophylaxisafteranteriorcruciateligamentreconstructionretrospectivecasecontrolstudy