Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling

Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling

IntroductionThe nuanced roles of neuropilin (NRP) isoforms, NRP1 and NRP2, have attracted considerable scientific interest regarding cancer progression. Their differential expressions across various cancer types are specific to NRP isoforms which are shown in a cancer type-dependent manner. It accou...

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Bibliographic Details
Main Authors: Hyun-Jee Han, Marcos Rubio-Alarcon, Thomas Allen, Sunwoo Lee, Taufiq Rahman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
neuropilin (NRP)
macrophage
single cell profiling
TME (tumor microenvironment)
ccRCC
SKCM
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1547330/full
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