Mining Chemical Activity Status from High-Throughput Screening Assays.

High-throughput screening (HTS) experiments provide a valuable resource that reports biological activity of numerous chemical compounds relative to their molecular targets. Building computational models that accurately predict such activity status (active vs. inactive) in specific assays is a challe...

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Bibliographic Details
Main Authors: Othman Soufan, Wail Ba-alawi, Moataz Afeef, Magbubah Essack, Valentin Rodionov, Panos Kalnis, Vladimir B Bajic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144426&type=printable
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