CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review

Background. Cytomegalovirus (CMV)- related gastroduodenal infection is rare in immunocompetent hosts, and although it is considered a self-limiting condition in most cases, there is scarce literature to assert its management. Case Presentation. We report a case of a 66-year-old immunocompetent male...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrawus Beany, Tova Rainis
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2021/3513223
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850172920242896896
author Andrawus Beany
Tova Rainis
author_facet Andrawus Beany
Tova Rainis
author_sort Andrawus Beany
collection DOAJ
description Background. Cytomegalovirus (CMV)- related gastroduodenal infection is rare in immunocompetent hosts, and although it is considered a self-limiting condition in most cases, there is scarce literature to assert its management. Case Presentation. We report a case of a 66-year-old immunocompetent male patient diagnosed with a giant gastric ulcer caused by CMV infection. The ulcer manifested as refractory vomiting and melena. Rapid and full resolution was observed on proton-pump inhibitor (PPI) monotherapy. Conclusion. Gastric CMV infection might mimic an advanced gastric tumor in individuals with an intact immune system. The condition is rare, and the diagnosis is challenging and oftentimes overlooked. However, a rapid resolution has been documented in all cases, even without antiviral therapy.
format Article
id doaj-art-cc6a4b905adf43bab67fec1fc1ad5bdc
institution OA Journals
issn 2090-6536
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Gastrointestinal Medicine
spelling doaj-art-cc6a4b905adf43bab67fec1fc1ad5bdc2025-08-20T02:19:57ZengWileyCase Reports in Gastrointestinal Medicine2090-65362021-01-01202110.1155/2021/3513223CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature ReviewAndrawus Beany0Tova Rainis1Division of GastroenterologyDivision of GastroenterologyBackground. Cytomegalovirus (CMV)- related gastroduodenal infection is rare in immunocompetent hosts, and although it is considered a self-limiting condition in most cases, there is scarce literature to assert its management. Case Presentation. We report a case of a 66-year-old immunocompetent male patient diagnosed with a giant gastric ulcer caused by CMV infection. The ulcer manifested as refractory vomiting and melena. Rapid and full resolution was observed on proton-pump inhibitor (PPI) monotherapy. Conclusion. Gastric CMV infection might mimic an advanced gastric tumor in individuals with an intact immune system. The condition is rare, and the diagnosis is challenging and oftentimes overlooked. However, a rapid resolution has been documented in all cases, even without antiviral therapy.http://dx.doi.org/10.1155/2021/3513223
spellingShingle Andrawus Beany
Tova Rainis
CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
Case Reports in Gastrointestinal Medicine
title CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
title_full CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
title_fullStr CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
title_full_unstemmed CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
title_short CMV-Related Gastric Ulcer and Gastroduodenitis in an Immunocompetent Patient: A Case Report and Literature Review
title_sort cmv related gastric ulcer and gastroduodenitis in an immunocompetent patient a case report and literature review
url http://dx.doi.org/10.1155/2021/3513223
work_keys_str_mv AT andrawusbeany cmvrelatedgastriculcerandgastroduodenitisinanimmunocompetentpatientacasereportandliteraturereview
AT tovarainis cmvrelatedgastriculcerandgastroduodenitisinanimmunocompetentpatientacasereportandliteraturereview