Neuroprotective Effect of PBCA Nanoparticles Delivering pEGFP-BDNF in a Mouse Model of Intracerebral Hemorrhage

Neuroprotective Effect of PBCA Nanoparticles Delivering pEGFP-BDNF in a Mouse Model of Intracerebral Hemorrhage

Objectives: Polybutylcyanoacrylate (PBCA) nanoparticles (NPs) were prepared by emulsion polymerization and loaded with an enhanced green fluorescent protein plasmid (pEGFP) encoding human brain-derived neurotrophic factor (BDNF). This study investigated the potential effects of PB...

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Bibliographic Details
Main Authors: Xue Lai, Yu Xiong, Xing Guo, Chunbo Chen
Format: Article
Language:English
Published: IMR Press 2025-05-01
Series:Journal of Integrative Neuroscience
Subjects:
intracerebral hemorrhage
polybutylcyanoacrylate nanoparticles
bdnf, blood-brain barrier
nf-κb signaling
Online Access:https://www.imrpress.com/journal/JIN/24/5/10.31083/JIN26971
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