Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial
Abstract Background Hospital-associated functional decline affects nearly one-third of the hospitalized older adults. The aim of this trial is to investigate the effect of a cognitive stimulation intervention provided via immersive virtual reality (IVR), with or without a multicomponent physical exe...
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BMC
2024-11-01
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| Series: | BMC Geriatrics |
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| Online Access: | https://doi.org/10.1186/s12877-024-05516-x |
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| author | Antón de la Casa-Marín Fabiola Zambom-Ferraresi Maria Cristina Ferrara Iranzu Ollo-Martínez Arkaitz Galbete Belén González-Glaría Débora Moral-Cuesta Itxaso Marín-Epelde Chenhui Chenhuichen Marta Lorente-Escudero Rodrigo Molero-de-Ávila Agurne García Baztán Fabricio Zambom-Ferraresi Nicolás Martínez-Velilla |
| author_facet | Antón de la Casa-Marín Fabiola Zambom-Ferraresi Maria Cristina Ferrara Iranzu Ollo-Martínez Arkaitz Galbete Belén González-Glaría Débora Moral-Cuesta Itxaso Marín-Epelde Chenhui Chenhuichen Marta Lorente-Escudero Rodrigo Molero-de-Ávila Agurne García Baztán Fabricio Zambom-Ferraresi Nicolás Martínez-Velilla |
| author_sort | Antón de la Casa-Marín |
| collection | DOAJ |
| description | Abstract Background Hospital-associated functional decline affects nearly one-third of the hospitalized older adults. The aim of this trial is to investigate the effect of a cognitive stimulation intervention provided via immersive virtual reality (IVR), with or without a multicomponent physical exercise intervention (ME) in hospitalized patients aged 75 or older with severe functional dependency at admission (Barthel Index < 60 points). Methods This clinical randomized controlled trial will be conducted in the Acute Geriatric Unit of a tertiary hospital in Spain. A total of 212 acute patients will be enrolled according to the following criteria: age ≥ 75, Barthel Index < 60, able to collaborate, expected length of stay ≥ 5 days, absence of clinical instability and severe dementia (Global Deterioration Scale 7) or other end-stage disease. Patients will be randomly assigned to a control group (CG) or any of the three intervention groups (IG): IVR, ME, or IVR + ME. The IVR group will watch ad-hoc videos showing Spanish regional landscapes and villages, approximately 4 min per day for three consecutive days. The ME group will undergo aerobic and strength exercise for progressive training of the upper and lower limbs. The IVR + ME group will do both cognitive and physical intervention. The primary outcomes will be cognitive and physical measures at discharge. Mood, quality of life, isometric strength, and acceptance of IVR will be also assessed. Discussion This project has the potential to enhance physical and psychological well-being of patients with severe functional dependency hospitalized for acute conditions, using technology. Virtual reality is expected to be favourably perceived by hospitalized older adults. This intervention represents a novelty in the geriatric patients’ care, comprising IVR and/or ME dispensed within the patient’s room, and including patients who are commonly excluded from research clinical trials. Trial registration This study was approved by the Navarra Clinical Research Ethics Committee on May 17th, 2023 (PI_2023/60). The trial is registered at ClinicalTrials.gov, registration number NCT06340282, 24th May 2024. |
| format | Article |
| id | doaj-art-cc64730e2e204abebd80d4008bf84177 |
| institution | OA Journals |
| issn | 1471-2318 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
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| series | BMC Geriatrics |
| spelling | doaj-art-cc64730e2e204abebd80d4008bf841772025-08-20T02:13:55ZengBMCBMC Geriatrics1471-23182024-11-0124111010.1186/s12877-024-05516-xEffects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trialAntón de la Casa-Marín0Fabiola Zambom-Ferraresi1Maria Cristina Ferrara2Iranzu Ollo-Martínez3Arkaitz Galbete4Belén González-Glaría5Débora Moral-Cuesta6Itxaso Marín-Epelde7Chenhui Chenhuichen8Marta Lorente-Escudero9Rodrigo Molero-de-Ávila10Agurne García Baztán11Fabricio Zambom-Ferraresi12Nicolás Martínez-Velilla13Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)School of Medicine and Surgery, University of Milan-BicoccaDepartment of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Statistics, Computer Science and Mathematics, Universidad Pública de Navarra (UPNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Department of Geriatric Medicine - Hospital Universitario de Navarra (HUN), Navarrabiomed, Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA)Abstract Background Hospital-associated functional decline affects nearly one-third of the hospitalized older adults. The aim of this trial is to investigate the effect of a cognitive stimulation intervention provided via immersive virtual reality (IVR), with or without a multicomponent physical exercise intervention (ME) in hospitalized patients aged 75 or older with severe functional dependency at admission (Barthel Index < 60 points). Methods This clinical randomized controlled trial will be conducted in the Acute Geriatric Unit of a tertiary hospital in Spain. A total of 212 acute patients will be enrolled according to the following criteria: age ≥ 75, Barthel Index < 60, able to collaborate, expected length of stay ≥ 5 days, absence of clinical instability and severe dementia (Global Deterioration Scale 7) or other end-stage disease. Patients will be randomly assigned to a control group (CG) or any of the three intervention groups (IG): IVR, ME, or IVR + ME. The IVR group will watch ad-hoc videos showing Spanish regional landscapes and villages, approximately 4 min per day for three consecutive days. The ME group will undergo aerobic and strength exercise for progressive training of the upper and lower limbs. The IVR + ME group will do both cognitive and physical intervention. The primary outcomes will be cognitive and physical measures at discharge. Mood, quality of life, isometric strength, and acceptance of IVR will be also assessed. Discussion This project has the potential to enhance physical and psychological well-being of patients with severe functional dependency hospitalized for acute conditions, using technology. Virtual reality is expected to be favourably perceived by hospitalized older adults. This intervention represents a novelty in the geriatric patients’ care, comprising IVR and/or ME dispensed within the patient’s room, and including patients who are commonly excluded from research clinical trials. Trial registration This study was approved by the Navarra Clinical Research Ethics Committee on May 17th, 2023 (PI_2023/60). The trial is registered at ClinicalTrials.gov, registration number NCT06340282, 24th May 2024.https://doi.org/10.1186/s12877-024-05516-xHospital-associated functional declineCognitive stimulationVirtual realityMulticomponent physical exerciseAcute careOlder adults |
| spellingShingle | Antón de la Casa-Marín Fabiola Zambom-Ferraresi Maria Cristina Ferrara Iranzu Ollo-Martínez Arkaitz Galbete Belén González-Glaría Débora Moral-Cuesta Itxaso Marín-Epelde Chenhui Chenhuichen Marta Lorente-Escudero Rodrigo Molero-de-Ávila Agurne García Baztán Fabricio Zambom-Ferraresi Nicolás Martínez-Velilla Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial BMC Geriatrics Hospital-associated functional decline Cognitive stimulation Virtual reality Multicomponent physical exercise Acute care Older adults |
| title | Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial |
| title_full | Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial |
| title_fullStr | Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial |
| title_full_unstemmed | Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial |
| title_short | Effects of immersive virtual reality stimulation and/or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency: study protocol for a randomized clinical trial |
| title_sort | effects of immersive virtual reality stimulation and or multicomponent physical exercise on cognitive and functional performance in hospitalized older patients with severe functional dependency study protocol for a randomized clinical trial |
| topic | Hospital-associated functional decline Cognitive stimulation Virtual reality Multicomponent physical exercise Acute care Older adults |
| url | https://doi.org/10.1186/s12877-024-05516-x |
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