Reliable protein–protein docking with AlphaFold, Rosetta, and replica exchange
Despite the recent breakthrough of AlphaFold (AF) in the field of protein sequence-to-structure prediction, modeling protein interfaces and predicting protein complex structures remains challenging, especially when there is a significant conformational change in one or both binding partners. Prior s...
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| Main Authors: | Ameya Harmalkar, Sergey Lyskov, Jeffrey J Gray |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2025-05-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/94029 |
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