Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection

Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection

This study aimed to investigate the impact of the ABCB1-rs1045642 gene polymorphism on the blood drug concentrations of voriconazole in patients with severe invasive fungal infections. A total of 101 patients treated with voriconazole were enrolled in this study. Polymerase chain reaction and Sanger...

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Bibliographic Details
Main Authors:	Qian Zhang, Xing Gao, Dongmei Lv
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Series:	Frontiers in Pharmacology
Subjects:	ABCB1-rs1045642 gene polymorphism inheritance voriconazole blood concentration invasive fungal infection
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1510890/full
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