Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease

Retroperitoneal fibrosis or Ormand's disease is rare in incidence and clinically elusive to diagnosis until obstructive uropathy clinically manifests by the mechanism of ureteral fibrotic strangulation and acute renal failure. We encountered a 50-year-old woman with months of nonspecific abdomi...

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Main Authors: Amarpreet Sandhu, Leslea Brickner, Mark Chen
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2011/302963
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author Amarpreet Sandhu
Leslea Brickner
Mark Chen
author_facet Amarpreet Sandhu
Leslea Brickner
Mark Chen
author_sort Amarpreet Sandhu
collection DOAJ
description Retroperitoneal fibrosis or Ormand's disease is rare in incidence and clinically elusive to diagnosis until obstructive uropathy clinically manifests by the mechanism of ureteral fibrotic strangulation and acute renal failure. We encountered a 50-year-old woman with months of nonspecific abdominal pain and presented with signs and symptoms of acute renal failure. Laboratory data was significant for blood urea nitrogen 47 mg/dL and creatinine of 8.47 mg/dL. Renal ultrasound revealed bilateral hydronephrosis and an abdominal computed tomogram confirmed an abnormal soft tissue retroperitoneal confluence that encased the pelvic vessels. Urologic consultation was requested and bilateral ureteral stents were placed with relief of her obstructive uropathy. Five days after ureteral stenting her creatinine dropped to 1.64 mg/dL. One month later patient underwent ureterolysis with biopsy showing fibroblast proliferation consistent with acute and chronic inflammation. By ruling out infections and malignancy, the final diagnosis was made to be idiopathic retroperitoneal fibrosis.
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spelling doaj-art-cc5b7015b7b54898b5def0ecadafff1b2025-08-20T03:19:32ZengWileyCase Reports in Nephrology2090-66412090-665X2011-01-01201110.1155/2011/302963302963Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's DiseaseAmarpreet Sandhu0Leslea Brickner1Mark Chen2Department of Medicine, Kaiser Permanente, Oakland, CA, USADepartment of Medicine, Kaiser Permanente, Oakland, CA, USADepartment of Medicine, Kaiser Permanente, Oakland, CA, USARetroperitoneal fibrosis or Ormand's disease is rare in incidence and clinically elusive to diagnosis until obstructive uropathy clinically manifests by the mechanism of ureteral fibrotic strangulation and acute renal failure. We encountered a 50-year-old woman with months of nonspecific abdominal pain and presented with signs and symptoms of acute renal failure. Laboratory data was significant for blood urea nitrogen 47 mg/dL and creatinine of 8.47 mg/dL. Renal ultrasound revealed bilateral hydronephrosis and an abdominal computed tomogram confirmed an abnormal soft tissue retroperitoneal confluence that encased the pelvic vessels. Urologic consultation was requested and bilateral ureteral stents were placed with relief of her obstructive uropathy. Five days after ureteral stenting her creatinine dropped to 1.64 mg/dL. One month later patient underwent ureterolysis with biopsy showing fibroblast proliferation consistent with acute and chronic inflammation. By ruling out infections and malignancy, the final diagnosis was made to be idiopathic retroperitoneal fibrosis.http://dx.doi.org/10.1155/2011/302963
spellingShingle Amarpreet Sandhu
Leslea Brickner
Mark Chen
Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
Case Reports in Nephrology
title Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
title_full Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
title_fullStr Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
title_full_unstemmed Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
title_short Ureteral Strangulation by Fibrosis: A Cold Case Report of Ormand's Disease
title_sort ureteral strangulation by fibrosis a cold case report of ormand s disease
url http://dx.doi.org/10.1155/2011/302963
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AT lesleabrickner ureteralstrangulationbyfibrosisacoldcasereportoformandsdisease
AT markchen ureteralstrangulationbyfibrosisacoldcasereportoformandsdisease