Coronary artery atherosclerosis in reproductive age group women-an autopsy study
Background: Atherosclerosis is the most common coronary artery disease (CAD). It leads to the blocking of arteries and myocardial infarction (MI). Many studies are focused on men. The aim of this study is to look at the prevalence of coronary atherosclerosis, its severity, and arteries involved in p...
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Manipal College of Medical Sciences, Pokhara
2024-12-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/68666 |
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| author | Chaithra R Jadhav Fremingston Marak Bharathi Pradeep |
| author_facet | Chaithra R Jadhav Fremingston Marak Bharathi Pradeep |
| author_sort | Chaithra R Jadhav |
| collection | DOAJ |
| description | Background: Atherosclerosis is the most common coronary artery disease (CAD). It leads to the blocking of arteries and myocardial infarction (MI). Many studies are focused on men. The aim of this study is to look at the prevalence of coronary atherosclerosis, its severity, and arteries involved in postmortem hearts in reproductive age group women.
Aims and Objectives: The objectives are (1) to estimate the occurrence of coronary atherosclerosis in reproductive age group women of 15–50 years. (2) To grade the atherosclerosis and stenosis. (3) To determine the cardiac changes associated. (4) To note the most common artery involved.
Materials and Methods: This study was autopsy-based retrospective study done for period of 3 years. From the autopsy forms, details such as age, gender, cause of death, and gross findings were noted. The sections from the left coronary artery (LCA), right coronary artery, left anterior descending (LAD), and circumflex artery (LCA) were reviewed microscopically to note the atherosclerotic grade and percentage of stenosis. Myocardium was reviewed for associated cardiac changes. Range, frequencies, percentage, and P-value were calculated. P<0.05 was taken statistically significant.
Results: Eighty-seven cases belonging to the reproductive age group of 15–50 years were categorized into 4 age groups. Type V American Heart Association atherosclerosis grade was seen more in women between 35 and 50 years. LAD was the most common artery to be involved. Eight cases showed acute MI.
Conclusions: Women of reproductive age group should be screened from 3rd decade onwards for CAD. |
| format | Article |
| id | doaj-art-cc4e56a53fd64d01bd20adfff9d21676 |
| institution | OA Journals |
| issn | 2467-9100 2091-0576 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj-art-cc4e56a53fd64d01bd20adfff9d216762025-08-20T02:30:43ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762024-12-011512145150https://doi.org/10.3126/ajms.v15i12.68666Coronary artery atherosclerosis in reproductive age group women-an autopsy studyChaithra R Jadhav 0https://orcid.org/0000-0002-2950-3539Fremingston Marak 1https://orcid.org/0000-0002-9361-3126Bharathi Pradeep 2https://orcid.org/0000-0002-7365-756XAssociate Professor, Department of Pathology, Indira Gandhi Medical College and Research Institute, Puducherry, India Professor and Head, Department of Pathology, Indira Gandhi Medical College and Research Institute, Puducherry, India Associate Professor, Department of Pathology, Indira Gandhi Medical College and Research Institute, Puducherry, India Background: Atherosclerosis is the most common coronary artery disease (CAD). It leads to the blocking of arteries and myocardial infarction (MI). Many studies are focused on men. The aim of this study is to look at the prevalence of coronary atherosclerosis, its severity, and arteries involved in postmortem hearts in reproductive age group women. Aims and Objectives: The objectives are (1) to estimate the occurrence of coronary atherosclerosis in reproductive age group women of 15–50 years. (2) To grade the atherosclerosis and stenosis. (3) To determine the cardiac changes associated. (4) To note the most common artery involved. Materials and Methods: This study was autopsy-based retrospective study done for period of 3 years. From the autopsy forms, details such as age, gender, cause of death, and gross findings were noted. The sections from the left coronary artery (LCA), right coronary artery, left anterior descending (LAD), and circumflex artery (LCA) were reviewed microscopically to note the atherosclerotic grade and percentage of stenosis. Myocardium was reviewed for associated cardiac changes. Range, frequencies, percentage, and P-value were calculated. P<0.05 was taken statistically significant. Results: Eighty-seven cases belonging to the reproductive age group of 15–50 years were categorized into 4 age groups. Type V American Heart Association atherosclerosis grade was seen more in women between 35 and 50 years. LAD was the most common artery to be involved. Eight cases showed acute MI. Conclusions: Women of reproductive age group should be screened from 3rd decade onwards for CAD.https://www.nepjol.info/index.php/AJMS/article/view/68666cardiovascular disease; coronary artery disease; myocardial infarction |
| spellingShingle | Chaithra R Jadhav Fremingston Marak Bharathi Pradeep Coronary artery atherosclerosis in reproductive age group women-an autopsy study Asian Journal of Medical Sciences cardiovascular disease; coronary artery disease; myocardial infarction |
| title | Coronary artery atherosclerosis in reproductive age group women-an autopsy study |
| title_full | Coronary artery atherosclerosis in reproductive age group women-an autopsy study |
| title_fullStr | Coronary artery atherosclerosis in reproductive age group women-an autopsy study |
| title_full_unstemmed | Coronary artery atherosclerosis in reproductive age group women-an autopsy study |
| title_short | Coronary artery atherosclerosis in reproductive age group women-an autopsy study |
| title_sort | coronary artery atherosclerosis in reproductive age group women an autopsy study |
| topic | cardiovascular disease; coronary artery disease; myocardial infarction |
| url | https://www.nepjol.info/index.php/AJMS/article/view/68666 |
| work_keys_str_mv | AT chaithrarjadhav coronaryarteryatherosclerosisinreproductiveagegroupwomenanautopsystudy AT fremingstonmarak coronaryarteryatherosclerosisinreproductiveagegroupwomenanautopsystudy AT bharathipradeep coronaryarteryatherosclerosisinreproductiveagegroupwomenanautopsystudy |