TREM 2 in Parkinson’s Disease: A Promising Candidate Gene for Disease Susceptibility and Progression

TREM 2 in Parkinson’s Disease: A Promising Candidate Gene for Disease Susceptibility and Progression

<b>Background/Objectives</b>: The activation of microglia and the activity of innate immunity have recently been recognized as part of Parkinson’s Disease (PD) pathophysiology. Triggering receptor expressed on myeloid cells 2 (TREM2) is a gene with neuroprotective roles. Its variations a...

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Bibliographic Details
Main Authors: Paolo Alonge, Carmela Rita Balistreri, Angelo Torrente, Daniele Magro, Elisa Rubino, Roberto Monastero
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Brain Sciences
Subjects:
TREM2
PD
Parkinson’s disease
neuroinflammation
microglia
neurodegenerative disorders
Online Access:https://www.mdpi.com/2076-3425/15/4/379
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