Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants

OBJECTIVE: We aimed to evaluate surfactant frequency and surfactant indications, as well as lung problems in late preterm infants. STUDY DESIGN: This retrospective and cross-sectional study was carried out by HSU Izmir Dr. Behcet Uz Pediatric Diseases and Surgery Research and Training Hospital. I...

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Main Authors: Ozlem Yilman, Senem Alkan Ozdemir, Sebnem Calkavur, Tulin Gokmen Yildirim
Format: Article
Language:English
Published: Medical Network 2023-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:https://gorm.com.tr/index.php/GORM/article/view/1440
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author Ozlem Yilman
Senem Alkan Ozdemir
Sebnem Calkavur
Tulin Gokmen Yildirim
author_facet Ozlem Yilman
Senem Alkan Ozdemir
Sebnem Calkavur
Tulin Gokmen Yildirim
author_sort Ozlem Yilman
collection DOAJ
description OBJECTIVE: We aimed to evaluate surfactant frequency and surfactant indications, as well as lung problems in late preterm infants. STUDY DESIGN: This retrospective and cross-sectional study was carried out by HSU Izmir Dr. Behcet Uz Pediatric Diseases and Surgery Research and Training Hospital. Infants who were born late preterm between January 2016 and January 2022 were hospitalized in the NICU due to respiratory distress in the first 24 hours. Lung problems and surfactant administration of these infants were evaluated. The frequency of surfactant dosages, their indications, and their effects were examined. As the control group, patients who were admitted to the NICU in the same period due to respiratory distress with similar indications but did not receive surfactant were considered. RESULTS: It was observed that surfactant was not administered to 105 infants and surfactant was administered to 106 infants. The median gestational week of the infants included in the study was 35 (34/36) weeks and the birth weight was 2185 (1780/2590) grams. A significant difference was observed in birth weight between the groups (p<0.001). Invasive ventilation was required in 52.1% of all cases and noninvasive ventilation was required in 33.6%. In the delivery room, the need for resuscitation and intubation was higher in the group requiring surfactant (p=0.001). The most common lung pathology in the surfactant group was RDS. CONCLUSION: It must not be forgotten that infants who are born late preterm infants are preterm infants and the evaluation of antenatal steroid administration must not be ignored.
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spelling doaj-art-cc44fd21c46c48eaae5a84af6c7884722025-02-11T21:17:49ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182023-12-0129310.21613/GORM.2023.1440Usage of Surfactant and Evaluation of Lung Problems in Late Preterm InfantsOzlem Yilman0Senem Alkan Ozdemir1Sebnem Calkavur2Tulin Gokmen Yildirim 3Department of Pediatrics, Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, University of Health Sciences Turkey, İzmir, TurkeyDivision of Neonatology, Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, University of Health Sciences Turkey, İzmir, TurkeyDivision of Neonatology, Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, University of Health Sciences Turkey, İzmir, TurkeyDivision of Neonatology, Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, University of Health Sciences Turkey, İzmir, Turkey OBJECTIVE: We aimed to evaluate surfactant frequency and surfactant indications, as well as lung problems in late preterm infants. STUDY DESIGN: This retrospective and cross-sectional study was carried out by HSU Izmir Dr. Behcet Uz Pediatric Diseases and Surgery Research and Training Hospital. Infants who were born late preterm between January 2016 and January 2022 were hospitalized in the NICU due to respiratory distress in the first 24 hours. Lung problems and surfactant administration of these infants were evaluated. The frequency of surfactant dosages, their indications, and their effects were examined. As the control group, patients who were admitted to the NICU in the same period due to respiratory distress with similar indications but did not receive surfactant were considered. RESULTS: It was observed that surfactant was not administered to 105 infants and surfactant was administered to 106 infants. The median gestational week of the infants included in the study was 35 (34/36) weeks and the birth weight was 2185 (1780/2590) grams. A significant difference was observed in birth weight between the groups (p<0.001). Invasive ventilation was required in 52.1% of all cases and noninvasive ventilation was required in 33.6%. In the delivery room, the need for resuscitation and intubation was higher in the group requiring surfactant (p=0.001). The most common lung pathology in the surfactant group was RDS. CONCLUSION: It must not be forgotten that infants who are born late preterm infants are preterm infants and the evaluation of antenatal steroid administration must not be ignored. https://gorm.com.tr/index.php/GORM/article/view/1440Late preterm PrematurityRespiratory distress syndromeSurfactant
spellingShingle Ozlem Yilman
Senem Alkan Ozdemir
Sebnem Calkavur
Tulin Gokmen Yildirim
Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
Gynecology Obstetrics & Reproductive Medicine
Late preterm
Prematurity
Respiratory distress syndrome
Surfactant
title Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
title_full Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
title_fullStr Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
title_full_unstemmed Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
title_short Usage of Surfactant and Evaluation of Lung Problems in Late Preterm Infants
title_sort usage of surfactant and evaluation of lung problems in late preterm infants
topic Late preterm
Prematurity
Respiratory distress syndrome
Surfactant
url https://gorm.com.tr/index.php/GORM/article/view/1440
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AT tulingokmenyildirim usageofsurfactantandevaluationoflungproblemsinlatepreterminfants