Evolution is in the details: Regulatory differences in modern human and Neanderthal
Transcription factor (TF) proteins play a critical role in the regulation of eukaryote gene expression via sequence-specific binding to genomic locations known as TF binding sites. We studied sites of genomic variation between modern human and Neanderthal promoters. We detected significant differenc...
Saved in:
| Main Authors: | Harlan R. Barker, Seppo Parkkila, Martti E.E. Tolvanen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037025002156 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sites
by: A. V. Tsukanov, et al.
Published: (2021-03-01) -
DNA–Protein Binding is Dominated by Short Anchoring Elements
by: Hong Chen, et al.
Published: (2025-05-01) -
Plasma cfDNA multi-omic biomarkers profiling for detection and stratification of gastric carcinoma
by: Shiyi Song, et al.
Published: (2025-06-01) -
Comparative Genomics and Phylogenetics of Chloroplasts Reveal Lower Rates of Genetic Variation in Mango (Mangifera)
by: Chuanning Li, et al.
Published: (2025-08-01) -
РАСКРЫТИЕ РЕГУЛЯТОРНОГО ПОТЕНЦИАЛА МИКРОСАТЕЛЛИТНЫХ ПОСЛЕДОВАТЕЛЬНОСТЕЙ IN SILICO В GLYCINE MAX (L.) MERR.
by: Пензин А.А., et al.
Published: (2025-06-01)