Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference

IntroductionWith the rapid decline in wild Bupleurum scorzonerifolium (BSW) resources, large-scale planting of cultivated B. scorzonerifolium (BSC) has begun. However, the effects of growth years on the quality of BSC, as well as the quality difference between BSC and BSW remain unclear.MethodsThis...

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Main Authors: Changsheng Yuan, Feng Zhou, Yihan Wang, Huaizhu Li, Yongliang Li, Shan Guan, Huaizhong Gao, Shikong Gao, Luqi Huang, Yanmeng Liu, Zhilai Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1552429/full
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author Changsheng Yuan
Feng Zhou
Yihan Wang
Huaizhu Li
Yongliang Li
Shan Guan
Huaizhong Gao
Shikong Gao
Luqi Huang
Yanmeng Liu
Zhilai Zhan
author_facet Changsheng Yuan
Feng Zhou
Yihan Wang
Huaizhu Li
Yongliang Li
Shan Guan
Huaizhong Gao
Shikong Gao
Luqi Huang
Yanmeng Liu
Zhilai Zhan
author_sort Changsheng Yuan
collection DOAJ
description IntroductionWith the rapid decline in wild Bupleurum scorzonerifolium (BSW) resources, large-scale planting of cultivated B. scorzonerifolium (BSC) has begun. However, the effects of growth years on the quality of BSC, as well as the quality difference between BSC and BSW remain unclear.MethodsThis study utilized trait characteristics, microstructure, cell wall components, sugar components, main pharmacological substances, metabolomics, and transcriptomics as key indicators and techniques, to comprehensively characterize and investigate the molecular mechanisms underlying the quality differences between BSC of different growth ages (1–3 years) and between BSC and BSW. Results and discussionAs the growth years increased, the root weight of BSC continuously increased, accompanied by root head expansion. Root length and middle and lower section diameters showed significant increases from 1 to 2 years, stabilizing from 2 to 3 years. The ratio of phloem width to xylem radius, along with the contents of total saponins and saikosaponins a, b2, c, and d, exhibited a trend of initial decrease, followed by an increase. Additionally, the number and size of oil cavities and ducts, as well as the volatile oil content, continuously increased. Metabolomic and transcriptomic analyses identified saponins and terpenoids as the primary differential components between different BSC growth years, with genes Bchns02G071080 and Bchns05G031860 (saponins) and Bchns01G03800 (terpenoids) identified as potential key regulatory genes. Furthermore, compared to the long-established, high-quality BSW, 3-year-old BSC (BSC3) showed the closest resemblance in morphological traits, microstructure, and chemical component content, particularly for key pharmacological substances, such as volatile oil, total saponins, and saikosaponins a, b2, c, and d. Considering both quality and economic benefits, BSC3 is recommended as a substitute for BSW. To the best of our knowledge, this is the first study to report the effects of growth years on the quality of BSC, offering valuable insights for guiding the artificial cultivation and quality assurance of B. scorzonerifolium.
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spelling doaj-art-cc41a24ce5df4cecb13445d67c902ad52025-08-20T03:06:25ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-03-011610.3389/fpls.2025.15524291552429Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a referenceChangsheng Yuan0Feng Zhou1Yihan Wang2Huaizhu Li3Yongliang Li4Shan Guan5Huaizhong Gao6Shikong Gao7Luqi Huang8Yanmeng Liu9Zhilai Zhan10State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaSchool of Chemistry and Chemical Engineering, Xianyang Normal University, Xianyang, ChinaShaanxi Health Guardian Liuwei Pharmaceutical Co., Ltd., Yulin, ChinaShaanxi Health Guardian Liuwei Pharmaceutical Co., Ltd., Yulin, ChinaNiuNiuShun Planting Farmers’ Professional Cooperative in Yuyang District, Yulin, ChinaShenmu Animal Husbandry Development Center, Yulin, ChinaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medica Sciences, Beijing, ChinaIntroductionWith the rapid decline in wild Bupleurum scorzonerifolium (BSW) resources, large-scale planting of cultivated B. scorzonerifolium (BSC) has begun. However, the effects of growth years on the quality of BSC, as well as the quality difference between BSC and BSW remain unclear.MethodsThis study utilized trait characteristics, microstructure, cell wall components, sugar components, main pharmacological substances, metabolomics, and transcriptomics as key indicators and techniques, to comprehensively characterize and investigate the molecular mechanisms underlying the quality differences between BSC of different growth ages (1–3 years) and between BSC and BSW. Results and discussionAs the growth years increased, the root weight of BSC continuously increased, accompanied by root head expansion. Root length and middle and lower section diameters showed significant increases from 1 to 2 years, stabilizing from 2 to 3 years. The ratio of phloem width to xylem radius, along with the contents of total saponins and saikosaponins a, b2, c, and d, exhibited a trend of initial decrease, followed by an increase. Additionally, the number and size of oil cavities and ducts, as well as the volatile oil content, continuously increased. Metabolomic and transcriptomic analyses identified saponins and terpenoids as the primary differential components between different BSC growth years, with genes Bchns02G071080 and Bchns05G031860 (saponins) and Bchns01G03800 (terpenoids) identified as potential key regulatory genes. Furthermore, compared to the long-established, high-quality BSW, 3-year-old BSC (BSC3) showed the closest resemblance in morphological traits, microstructure, and chemical component content, particularly for key pharmacological substances, such as volatile oil, total saponins, and saikosaponins a, b2, c, and d. Considering both quality and economic benefits, BSC3 is recommended as a substitute for BSW. To the best of our knowledge, this is the first study to report the effects of growth years on the quality of BSC, offering valuable insights for guiding the artificial cultivation and quality assurance of B. scorzonerifolium. https://www.frontiersin.org/articles/10.3389/fpls.2025.1552429/fullBupleurum scorzonerifoliumgrowth yearschemical composition differencestranscriptomics and metabolomicsquality differencemolecular mechanisms
spellingShingle Changsheng Yuan
Feng Zhou
Yihan Wang
Huaizhu Li
Yongliang Li
Shan Guan
Huaizhong Gao
Shikong Gao
Luqi Huang
Yanmeng Liu
Zhilai Zhan
Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
Frontiers in Plant Science
Bupleurum scorzonerifolium
growth years
chemical composition differences
transcriptomics and metabolomics
quality difference
molecular mechanisms
title Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
title_full Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
title_fullStr Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
title_full_unstemmed Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
title_short Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference
title_sort effects of growth years on the quality of cultivated bupleurum scorzonerifolium roots with wild bupleurum scorzonerifolium roots as a reference
topic Bupleurum scorzonerifolium
growth years
chemical composition differences
transcriptomics and metabolomics
quality difference
molecular mechanisms
url https://www.frontiersin.org/articles/10.3389/fpls.2025.1552429/full
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