Occurrence of virulence genes icaADBC and antibiotic resistance genes blaZ, mecA, and aac(6’)-Ie-aph (2’’)-Ia in coagulase-negative staphylococci isolates from neonates with sepsis at a regional referral hospital in Dar es Salaam, Tanzania

Occurrence of virulence genes icaADBC and antibiotic resistance genes blaZ, mecA, and aac(6’)-Ie-aph (2’’)-Ia in coagulase-negative staphylococci isolates from neonates with sepsis at a regional referral hospital in Dar es Salaam, Tanzania

Abstract Background Coagulase-negative staphylococci (CoNS) have been linked to severe conditions such as bloodstream infection, with biofilm formation regarded as the major virulence mechanism. This study determined virulence genes (VGs) (icaA, icaB, icaC, and icaD) responsible for biofilm formatio...

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Main Authors: Anjela John Charles, Mtebe Majigo, Jackline E. Makupa, Upendo Kibwana, Zivonishe Mwazyunga, Ambele M. Mwandigha, Elieshiupendo M. Niccodem, Joel Efraim, Nyambura Moremi, Joel Manyahi, Doreen Kamori, Mecky I. Matee, Agricola Joachim
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:Bulletin of the National Research Centre
Subjects:
CoNS
Antibiotic resistance
Virulence genes
Neonates
Sepsis
Online Access:https://doi.org/10.1186/s42269-024-01271-6
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