Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications
Organic electrochemical transistors (OECTs), as an emerging device for the development of novel biosensors, have attracted more and more attention in recent years, demonstrating their promising prospects and commercial potential. Functional OECTs have been widely applied in the field of biosensors d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-11-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/12/11/236 |
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| author | Zhiyao Wang Minggao Liu Yundi Zhao Yating Chen Beenish Noureen Liping Du Chunsheng Wu |
| author_facet | Zhiyao Wang Minggao Liu Yundi Zhao Yating Chen Beenish Noureen Liping Du Chunsheng Wu |
| author_sort | Zhiyao Wang |
| collection | DOAJ |
| description | Organic electrochemical transistors (OECTs), as an emerging device for the development of novel biosensors, have attracted more and more attention in recent years, demonstrating their promising prospects and commercial potential. Functional OECTs have been widely applied in the field of biosensors due to their decisive advantages, such as high transconductance, easy functionalization, and high integration capability. Therefore, this review aims to provide a comprehensive summary of the most recent advances in the application of functional OECT-based biosensors in biomedicine, especially focusing on those biosensors for the detection of physiological and biochemical parameters that are critical for the health of human beings. First, the main components and basic working principles of OECTs will be briefly introduced. In the following, the strategies and key technologies for the preparation of functional OECT-based biosensors will be outlined and discussed with regard to the applications of the detection of various targets, including metabolites, ions, neurotransmitters, electrophysiological parameters, and immunological molecules. Finally, the current main issues and future development trends of functional OECT-based biosensors will be proposed and discussed. The breakthrough in functional OECT-based biosensors is believed to enable such devices to achieve higher performance, and thus, this technology could provide new insight into the future field of medical and life sciences. |
| format | Article |
| id | doaj-art-cc206f41a0e843e7bbcb1fc26f676e4a |
| institution | Kabale University |
| issn | 2227-9040 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj-art-cc206f41a0e843e7bbcb1fc26f676e4a2024-11-26T17:57:13ZengMDPI AGChemosensors2227-90402024-11-01121123610.3390/chemosensors12110236Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical ApplicationsZhiyao Wang0Minggao Liu1Yundi Zhao2Yating Chen3Beenish Noureen4Liping Du5Chunsheng Wu6Institute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaInstitute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, ChinaOrganic electrochemical transistors (OECTs), as an emerging device for the development of novel biosensors, have attracted more and more attention in recent years, demonstrating their promising prospects and commercial potential. Functional OECTs have been widely applied in the field of biosensors due to their decisive advantages, such as high transconductance, easy functionalization, and high integration capability. Therefore, this review aims to provide a comprehensive summary of the most recent advances in the application of functional OECT-based biosensors in biomedicine, especially focusing on those biosensors for the detection of physiological and biochemical parameters that are critical for the health of human beings. First, the main components and basic working principles of OECTs will be briefly introduced. In the following, the strategies and key technologies for the preparation of functional OECT-based biosensors will be outlined and discussed with regard to the applications of the detection of various targets, including metabolites, ions, neurotransmitters, electrophysiological parameters, and immunological molecules. Finally, the current main issues and future development trends of functional OECT-based biosensors will be proposed and discussed. The breakthrough in functional OECT-based biosensors is believed to enable such devices to achieve higher performance, and thus, this technology could provide new insight into the future field of medical and life sciences.https://www.mdpi.com/2227-9040/12/11/236organic electrochemical transistorbiosensorfunctional devicebiomedicinebioanalysis |
| spellingShingle | Zhiyao Wang Minggao Liu Yundi Zhao Yating Chen Beenish Noureen Liping Du Chunsheng Wu Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications Chemosensors organic electrochemical transistor biosensor functional device biomedicine bioanalysis |
| title | Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications |
| title_full | Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications |
| title_fullStr | Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications |
| title_full_unstemmed | Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications |
| title_short | Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications |
| title_sort | functional organic electrochemical transistor based biosensors for biomedical applications |
| topic | organic electrochemical transistor biosensor functional device biomedicine bioanalysis |
| url | https://www.mdpi.com/2227-9040/12/11/236 |
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