Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps
Ensuring consistent drug concentration during intravenous (IV) administration is essential for patient safety in intensive care units (ICUs). Standard syringe pumps are prone to concentration variability due to sedimentation, molecular aggregation, and drug adsorption on plastic surfaces, especially...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/15/13/7277 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849704366844411904 |
|---|---|
| author | Dumitru Adrian Draghici Angela Repanovici |
| author_facet | Dumitru Adrian Draghici Angela Repanovici |
| author_sort | Dumitru Adrian Draghici |
| collection | DOAJ |
| description | Ensuring consistent drug concentration during intravenous (IV) administration is essential for patient safety in intensive care units (ICUs). Standard syringe pumps are prone to concentration variability due to sedimentation, molecular aggregation, and drug adsorption on plastic surfaces, especially during prolonged, low-rate infusions. We propose a novel mechatronic homogenization system integrated into syringe pumps, which combines dual-axis vibration, low-power eccentric motors, and a two-stage photonic treatment mechanism to maintain drug stability. The system is theoretically modeled and experimentally validated across multiple drug classes. Results show a significant reduction in concentration variability by over 90% compared to conventional syringe pumps, demonstrating strong potential for clinical impact. However, the study was conducted on a small class of drugs and requires a diversification of the classes of drugs that are subject to the experiment, especially in photonic treatment, where the effects on other classes of drugs administered intravenously are not fully known. |
| format | Article |
| id | doaj-art-cc1fe96c020f4bc99e4e0d1013e1bb06 |
| institution | DOAJ |
| issn | 2076-3417 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj-art-cc1fe96c020f4bc99e4e0d1013e1bb062025-08-20T03:16:46ZengMDPI AGApplied Sciences2076-34172025-06-011513727710.3390/app15137277Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe PumpsDumitru Adrian Draghici0Angela Repanovici1Faculty of Product Design and Environment, Transilvania University of Brasov, 500036 Brașov, RomaniaFaculty of Product Design and Environment, Transilvania University of Brasov, 500036 Brașov, RomaniaEnsuring consistent drug concentration during intravenous (IV) administration is essential for patient safety in intensive care units (ICUs). Standard syringe pumps are prone to concentration variability due to sedimentation, molecular aggregation, and drug adsorption on plastic surfaces, especially during prolonged, low-rate infusions. We propose a novel mechatronic homogenization system integrated into syringe pumps, which combines dual-axis vibration, low-power eccentric motors, and a two-stage photonic treatment mechanism to maintain drug stability. The system is theoretically modeled and experimentally validated across multiple drug classes. Results show a significant reduction in concentration variability by over 90% compared to conventional syringe pumps, demonstrating strong potential for clinical impact. However, the study was conducted on a small class of drugs and requires a diversification of the classes of drugs that are subject to the experiment, especially in photonic treatment, where the effects on other classes of drugs administered intravenously are not fully known.https://www.mdpi.com/2076-3417/15/13/7277syringepumpsdrughomogeneitylinearinfusion |
| spellingShingle | Dumitru Adrian Draghici Angela Repanovici Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps Applied Sciences syringe pumps drug homogeneity linear infusion |
| title | Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps |
| title_full | Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps |
| title_fullStr | Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps |
| title_full_unstemmed | Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps |
| title_short | Mechatronic System for Maintaining the Homogeneity of Injectable Drugs in Syringe Pumps |
| title_sort | mechatronic system for maintaining the homogeneity of injectable drugs in syringe pumps |
| topic | syringe pumps drug homogeneity linear infusion |
| url | https://www.mdpi.com/2076-3417/15/13/7277 |
| work_keys_str_mv | AT dumitruadriandraghici mechatronicsystemformaintainingthehomogeneityofinjectabledrugsinsyringepumps AT angelarepanovici mechatronicsystemformaintainingthehomogeneityofinjectabledrugsinsyringepumps |