Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy
Aim. To compare the measurements of retinal nerve fiber layer (RNFL), macula and optic disc parameters obtained by optical coherence tomography (OCT), and intraocular pressure (IOP) between the patients with thyroid-associated ophthalmopathy (TAO) and healthy controls. Methods. One hundred and thirt...
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| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/9452687 |
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| author | Osman Sayın Volkan Yeter Nurşen Arıtürk |
| author_facet | Osman Sayın Volkan Yeter Nurşen Arıtürk |
| author_sort | Osman Sayın |
| collection | DOAJ |
| description | Aim. To compare the measurements of retinal nerve fiber layer (RNFL), macula and optic disc parameters obtained by optical coherence tomography (OCT), and intraocular pressure (IOP) between the patients with thyroid-associated ophthalmopathy (TAO) and healthy controls. Methods. One hundred and thirty-two eyes of 66 patients with TAO and 72 eyes of 36 healthy controls were included in the study. Proptosis level was determined by Hertel exophthalmometer. Optic disc, peripapillary retinal nerve fiber layer, and macula parameters were measured by OCT. All measurements of the patients were compared with those of age- and sex-matched healthy controls. Results. No statistically significant difference was found between the patients with TAO and control group in terms of demographic characteristics (P>0.05). Exophthalmometer measurements and IOP were higher in TAO group (P<0.05). Mean macula thicknesses in TAO and control groups were 239.3±29.8 μm and 246.6±31.8 μm, respectively, and the difference between the groups was statistically significant (P=0.000). TAO group had thinner inferior RNFL thickness and macular thicknesses (superior, inferior, temporal, and nasal) and higher disc area and C/D ratio when compared with the control group (P<0.05). Conclusion. IOP, disc area, and C/D area ratio were higher in the patients with TAO and the thicknesses of macula and inferior RNFL were thinner when compared with healthy controls. This trial is registered with registration number at clinicaltrials.gov NCT02766660. |
| format | Article |
| id | doaj-art-cc1f6f7fd1e448cb998fa724db304d33 |
| institution | OA Journals |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-cc1f6f7fd1e448cb998fa724db304d332025-08-20T02:19:57ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/94526879452687Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated OphthalmopathyOsman Sayın0Volkan Yeter1Nurşen Arıtürk2Department of Ophthalmology, Beyhekim State Hospital, Konya, TurkeyDepartment of Ophthalmology, NEON Hospital, 24100 Erzincan, TurkeyDepartment of Ophthalmology, Ondokuz Mayıs University, Samsun, TurkeyAim. To compare the measurements of retinal nerve fiber layer (RNFL), macula and optic disc parameters obtained by optical coherence tomography (OCT), and intraocular pressure (IOP) between the patients with thyroid-associated ophthalmopathy (TAO) and healthy controls. Methods. One hundred and thirty-two eyes of 66 patients with TAO and 72 eyes of 36 healthy controls were included in the study. Proptosis level was determined by Hertel exophthalmometer. Optic disc, peripapillary retinal nerve fiber layer, and macula parameters were measured by OCT. All measurements of the patients were compared with those of age- and sex-matched healthy controls. Results. No statistically significant difference was found between the patients with TAO and control group in terms of demographic characteristics (P>0.05). Exophthalmometer measurements and IOP were higher in TAO group (P<0.05). Mean macula thicknesses in TAO and control groups were 239.3±29.8 μm and 246.6±31.8 μm, respectively, and the difference between the groups was statistically significant (P=0.000). TAO group had thinner inferior RNFL thickness and macular thicknesses (superior, inferior, temporal, and nasal) and higher disc area and C/D ratio when compared with the control group (P<0.05). Conclusion. IOP, disc area, and C/D area ratio were higher in the patients with TAO and the thicknesses of macula and inferior RNFL were thinner when compared with healthy controls. This trial is registered with registration number at clinicaltrials.gov NCT02766660.http://dx.doi.org/10.1155/2016/9452687 |
| spellingShingle | Osman Sayın Volkan Yeter Nurşen Arıtürk Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy Journal of Ophthalmology |
| title | Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy |
| title_full | Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy |
| title_fullStr | Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy |
| title_full_unstemmed | Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy |
| title_short | Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy |
| title_sort | optic disc macula and retinal nerve fiber layer measurements obtained by oct in thyroid associated ophthalmopathy |
| url | http://dx.doi.org/10.1155/2016/9452687 |
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