Cutaneous approach in toxic epidermal necrolysis
INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality. The care of the mucous lesions and skin and a multidisciplinary approach are very important for the prognosis and future sequelae....
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2017-03-01
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| Series: | Revista Brasileira de Cirurgia Plástica |
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| Online Access: | http://www.rbcp.org.br/export-pdf/1823/en_v32n1a18.pdf |
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| author | Francisco Carlos Santos Neto Pedro Salomão Piccinini Jean Miguel Andary Lucas Dal Pozzo Sartori Lucas Tomkowski Cancian Carlos Oscar Uebel Milton Paulo de Oliveira |
| author_facet | Francisco Carlos Santos Neto Pedro Salomão Piccinini Jean Miguel Andary Lucas Dal Pozzo Sartori Lucas Tomkowski Cancian Carlos Oscar Uebel Milton Paulo de Oliveira |
| author_sort | Francisco Carlos Santos Neto |
| collection | DOAJ |
| description | INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality. The care of the mucous lesions and skin and a multidisciplinary approach are very important for the prognosis and future sequelae.
OBJECTIVES: To discuss the main aspects of this syndrome through a literature review illustrated by a clinical case. Methods: Review of the literature using the PubMed and SciELO online databases was performed. Articles in English, Portuguese, French, and Spanish were included and illustrated with a pediatric clinical case. The keywords used were as follows: "toxic epidermal necrolysis," "Stevens-Johnson overlap," "necrólise epidérmica tóxica," and "síndrome Stevens-Johnson."
RESULTS: We presented data to guide the management of patients with toxic epidermal necrolysis for plastic surgeons, pediatricians, intensivists, dermatologists, and emergency physicians. The case treated had a favorable disease course without sequelae.
CONCLUSION: A high level of suspicion is necessary for an adequate diagnosis and risk stratification, and early support measures and treatment should be performed by a multidisciplinary team trained to minimize damage and mortality. |
| format | Article |
| id | doaj-art-cc00c80d6a3047d49baa94df2d481fca |
| institution | Kabale University |
| issn | 1983-5175 2177-1235 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Revista Brasileira de Cirurgia Plástica |
| spelling | doaj-art-cc00c80d6a3047d49baa94df2d481fca2025-08-20T03:58:54ZengThieme Revinter Publicações Ltda.Revista Brasileira de Cirurgia Plástica1983-51752177-12352017-03-01320112813410.5935/2177-1235.2017RBCP0018Cutaneous approach in toxic epidermal necrolysisFrancisco Carlos Santos Neto0Pedro Salomão Piccinini1Jean Miguel Andary2Lucas Dal Pozzo Sartori3Lucas Tomkowski Cancian4Carlos Oscar Uebel5Milton Paulo de Oliveira6Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilHospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, BrazilINTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality. The care of the mucous lesions and skin and a multidisciplinary approach are very important for the prognosis and future sequelae. OBJECTIVES: To discuss the main aspects of this syndrome through a literature review illustrated by a clinical case. Methods: Review of the literature using the PubMed and SciELO online databases was performed. Articles in English, Portuguese, French, and Spanish were included and illustrated with a pediatric clinical case. The keywords used were as follows: "toxic epidermal necrolysis," "Stevens-Johnson overlap," "necrólise epidérmica tóxica," and "síndrome Stevens-Johnson." RESULTS: We presented data to guide the management of patients with toxic epidermal necrolysis for plastic surgeons, pediatricians, intensivists, dermatologists, and emergency physicians. The case treated had a favorable disease course without sequelae. CONCLUSION: A high level of suspicion is necessary for an adequate diagnosis and risk stratification, and early support measures and treatment should be performed by a multidisciplinary team trained to minimize damage and mortality.http://www.rbcp.org.br/export-pdf/1823/en_v32n1a18.pdfdermatologyexanthemastevens-johnson syndromesurgical procedureschild |
| spellingShingle | Francisco Carlos Santos Neto Pedro Salomão Piccinini Jean Miguel Andary Lucas Dal Pozzo Sartori Lucas Tomkowski Cancian Carlos Oscar Uebel Milton Paulo de Oliveira Cutaneous approach in toxic epidermal necrolysis Revista Brasileira de Cirurgia Plástica dermatology exanthema stevens-johnson syndrome surgical procedures child |
| title | Cutaneous approach in toxic epidermal
necrolysis |
| title_full | Cutaneous approach in toxic epidermal
necrolysis |
| title_fullStr | Cutaneous approach in toxic epidermal
necrolysis |
| title_full_unstemmed | Cutaneous approach in toxic epidermal
necrolysis |
| title_short | Cutaneous approach in toxic epidermal
necrolysis |
| title_sort | cutaneous approach in toxic epidermal necrolysis |
| topic | dermatology exanthema stevens-johnson syndrome surgical procedures child |
| url | http://www.rbcp.org.br/export-pdf/1823/en_v32n1a18.pdf |
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