NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives
An efficient catalytic protocol for the synthesis of novel spiro[indoline-3,4′-pyrano[2,3-c]thiazole]carbonitriles and condensed thiazolo[5′′,4′′:5′,6′]pyrano[4′,3′:3,4]furo[2,3-b]indole derivatives is developed in a one-pot three-component approach involving substituted 1H-indole-2,3-diones, activ...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/606259 |
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| author | Harshita Sachdeva Diksha Dwivedi R. R. Bhattacharjee Sarita Khaturia Rekha Saroj |
| author_facet | Harshita Sachdeva Diksha Dwivedi R. R. Bhattacharjee Sarita Khaturia Rekha Saroj |
| author_sort | Harshita Sachdeva |
| collection | DOAJ |
| description | An efficient catalytic protocol for the synthesis of novel spiro[indoline-3,4′-pyrano[2,3-c]thiazole]carbonitriles and condensed thiazolo[5′′,4′′:5′,6′]pyrano[4′,3′:3,4]furo[2,3-b]indole derivatives is developed in a one-pot three-component approach involving substituted 1H-indole-2,3-diones, activated methylene reagent, and 2-thioxo-4-thiazolidinone under conventional heating and microwave irradiation. This paper describes the use of NiO nanoparticles as catalyst for the synthesis of novel spiro and condensed indole derivatives by Knoevenagel condensation followed by Michael addition. The advantageous features of this methodology are operational simplicity, high yield processing, and easy handling. The particle size of NiO nanoparticle was determined by XRD. After reaction course, NiO nanoparticles can be recycled and reused without any apparent loss of activity. |
| format | Article |
| id | doaj-art-cc008a58da6a40c4912eccfa8b317d4d |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-cc008a58da6a40c4912eccfa8b317d4d2025-02-03T07:24:48ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/606259606259NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole DerivativesHarshita Sachdeva0Diksha Dwivedi1R. R. Bhattacharjee2Sarita Khaturia3Rekha Saroj4Department of Chemistry, Faculty of Engineering and Technology, Mody Institute of Technology and Science, Sikar, Rajasthan, Lakshmangarh 332311, IndiaDepartment of Chemistry, Faculty of Engineering and Technology, Mody Institute of Technology and Science, Sikar, Rajasthan, Lakshmangarh 332311, IndiaDepartment of Chemistry, Faculty of Engineering and Technology, Mody Institute of Technology and Science, Sikar, Rajasthan, Lakshmangarh 332311, IndiaDepartment of Chemistry, Faculty of Engineering and Technology, Mody Institute of Technology and Science, Sikar, Rajasthan, Lakshmangarh 332311, IndiaDepartment of Chemistry, Faculty of Engineering and Technology, Mody Institute of Technology and Science, Sikar, Rajasthan, Lakshmangarh 332311, IndiaAn efficient catalytic protocol for the synthesis of novel spiro[indoline-3,4′-pyrano[2,3-c]thiazole]carbonitriles and condensed thiazolo[5′′,4′′:5′,6′]pyrano[4′,3′:3,4]furo[2,3-b]indole derivatives is developed in a one-pot three-component approach involving substituted 1H-indole-2,3-diones, activated methylene reagent, and 2-thioxo-4-thiazolidinone under conventional heating and microwave irradiation. This paper describes the use of NiO nanoparticles as catalyst for the synthesis of novel spiro and condensed indole derivatives by Knoevenagel condensation followed by Michael addition. The advantageous features of this methodology are operational simplicity, high yield processing, and easy handling. The particle size of NiO nanoparticle was determined by XRD. After reaction course, NiO nanoparticles can be recycled and reused without any apparent loss of activity.http://dx.doi.org/10.1155/2013/606259 |
| spellingShingle | Harshita Sachdeva Diksha Dwivedi R. R. Bhattacharjee Sarita Khaturia Rekha Saroj NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives Journal of Chemistry |
| title | NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives |
| title_full | NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives |
| title_fullStr | NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives |
| title_full_unstemmed | NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives |
| title_short | NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives |
| title_sort | nio nanoparticles an efficient catalyst for the multicomponent one pot synthesis of novel spiro and condensed indole derivatives |
| url | http://dx.doi.org/10.1155/2013/606259 |
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