A roadmap for personalized medicine: the findings of the IC2PerMed project

IntroductionPersonalized Medicine (PM) tailors prevention and treatment to individuals based on their unique characteristics. It has the potential to improve health outcomes and healthcare sustainability by optimizing resource allocation. Both the European Union (EU) and China have prioritized PM in...

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Main Authors: Flavia Beccia, Francesco Andrea Causio, Marzia Di Marcantonio, Ilda Hoxhaj, Chiara Cadeddu, Melissa Campagno, Lena Schleicher, Carmen Fotino, Maike Tauchert, Marta Lomazzi, Lili Wang, Wenya Wang, Huiyao Huang, Walter Ricciardi, Stefania Boccia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1572921/full
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author Flavia Beccia
Francesco Andrea Causio
Marzia Di Marcantonio
Ilda Hoxhaj
Chiara Cadeddu
Melissa Campagno
Lena Schleicher
Carmen Fotino
Maike Tauchert
Marta Lomazzi
Lili Wang
Wenya Wang
Huiyao Huang
Walter Ricciardi
Stefania Boccia
Stefania Boccia
author_facet Flavia Beccia
Francesco Andrea Causio
Marzia Di Marcantonio
Ilda Hoxhaj
Chiara Cadeddu
Melissa Campagno
Lena Schleicher
Carmen Fotino
Maike Tauchert
Marta Lomazzi
Lili Wang
Wenya Wang
Huiyao Huang
Walter Ricciardi
Stefania Boccia
Stefania Boccia
author_sort Flavia Beccia
collection DOAJ
description IntroductionPersonalized Medicine (PM) tailors prevention and treatment to individuals based on their unique characteristics. It has the potential to improve health outcomes and healthcare sustainability by optimizing resource allocation. Both the European Union (EU) and China have prioritized PM in their health strategies. The IC2PerMed project was established to foster collaboration between the EU and China by developing a joint PM roadmap.MethodsTo assess the state of PM in the EU and China, the project conducted a comprehensive mapping of relevant policies, programs, funding mechanisms, and health ecosystems. Additionally, three Delphi surveys were carried out, identifying 65 priorities, which were synthesized into a set of strategic actions.ResultsThe main output of the project is a joint roadmap for implementing PM in the EU and China. The roadmap promotes best practice exchange and addresses potential barriers to PM adoption. It outlines structural actions including enhancing health literacy, fostering intersectoral and international collaboration, ongoing review of emerging technologies, and facilitating innovation market entry through needs assessment and Health Technology Assessment. Key enablers such as data interoperability and shared standards are highlighted, along with ethical, social, and regulatory considerations that are universally relevant to PM implementation.DiscussionA shared action plan can guide health policy and help policymakers understand the interconnection between healthcare, the economy, and society. By supporting international projects and investing in research and innovation, stakeholders can advance global healthcare.
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spelling doaj-art-cbfbae2e64934affb73c1015b91cd7762025-08-20T03:56:09ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.15729211572921A roadmap for personalized medicine: the findings of the IC2PerMed projectFlavia Beccia0Francesco Andrea Causio1Marzia Di Marcantonio2Ilda Hoxhaj3Chiara Cadeddu4Melissa Campagno5Lena Schleicher6Carmen Fotino7Maike Tauchert8Marta Lomazzi9Lili Wang10Wenya Wang11Huiyao Huang12Walter Ricciardi13Stefania Boccia14Stefania Boccia15Section of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, ItalySection of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, ItalyFaculty of Economics, Università Cattolica del Sacro Cuore, Rome, ItalyDepartment of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, ItalyErasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, NetherlandsG.A.C. Group - Innovation and Performance for Impact, Valbonne, FranceSteinbeis Europa Zentrum (SEZ), Stuttgart, GermanyFondazione Telethon, Milan, ItalyBBMRI-ERIC, Graz, AustriaWorld Federation of Public Health Associations (WFPHA), Geneva, Switzerland0Jingyi Alliance Clinical Application; BGI, Beijing, China1Center of Biotherapy, Beijing Tsinghua Changgang Hospital, Tsinghua University, Beijing, China2Academic Director, Clinical Trials Center of National Cancer Center, Beijing, ChinaSection of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, ItalySection of Hygiene, Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy3Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, ItalyIntroductionPersonalized Medicine (PM) tailors prevention and treatment to individuals based on their unique characteristics. It has the potential to improve health outcomes and healthcare sustainability by optimizing resource allocation. Both the European Union (EU) and China have prioritized PM in their health strategies. The IC2PerMed project was established to foster collaboration between the EU and China by developing a joint PM roadmap.MethodsTo assess the state of PM in the EU and China, the project conducted a comprehensive mapping of relevant policies, programs, funding mechanisms, and health ecosystems. Additionally, three Delphi surveys were carried out, identifying 65 priorities, which were synthesized into a set of strategic actions.ResultsThe main output of the project is a joint roadmap for implementing PM in the EU and China. The roadmap promotes best practice exchange and addresses potential barriers to PM adoption. It outlines structural actions including enhancing health literacy, fostering intersectoral and international collaboration, ongoing review of emerging technologies, and facilitating innovation market entry through needs assessment and Health Technology Assessment. Key enablers such as data interoperability and shared standards are highlighted, along with ethical, social, and regulatory considerations that are universally relevant to PM implementation.DiscussionA shared action plan can guide health policy and help policymakers understand the interconnection between healthcare, the economy, and society. By supporting international projects and investing in research and innovation, stakeholders can advance global healthcare.https://www.frontiersin.org/articles/10.3389/fmed.2025.1572921/fullpersonalized medicineroadmapChinaEuropean Unionpriorities
spellingShingle Flavia Beccia
Francesco Andrea Causio
Marzia Di Marcantonio
Ilda Hoxhaj
Chiara Cadeddu
Melissa Campagno
Lena Schleicher
Carmen Fotino
Maike Tauchert
Marta Lomazzi
Lili Wang
Wenya Wang
Huiyao Huang
Walter Ricciardi
Stefania Boccia
Stefania Boccia
A roadmap for personalized medicine: the findings of the IC2PerMed project
Frontiers in Medicine
personalized medicine
roadmap
China
European Union
priorities
title A roadmap for personalized medicine: the findings of the IC2PerMed project
title_full A roadmap for personalized medicine: the findings of the IC2PerMed project
title_fullStr A roadmap for personalized medicine: the findings of the IC2PerMed project
title_full_unstemmed A roadmap for personalized medicine: the findings of the IC2PerMed project
title_short A roadmap for personalized medicine: the findings of the IC2PerMed project
title_sort roadmap for personalized medicine the findings of the ic2permed project
topic personalized medicine
roadmap
China
European Union
priorities
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1572921/full
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