Antigen delivery by filamentous bacteriophage fd displaying an anti‐DEC‐205 single‐chain variable fragment confers adjuvanticity by triggering a TLR9‐mediated immune response
Abstract Filamentous bacteriophage fd particles delivering antigenic determinants via DEC‐205 (fdsc‐αDEC) represent a powerful delivery system that induces CD8+ T‐cell responses even when administered in the absence of adjuvants or maturation stimuli for dendritic cells. In order to investigate the...
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| Main Authors: | Rossella Sartorius, Luciana D'Apice, Maria Trovato, Fausta Cuccaro, Valerio Costa, Maria Giovanna De Leo, Vincenzo Manuel Marzullo, Carmelo Biondo, Sabato D'Auria, Maria Antonietta De Matteis, Alfredo Ciccodicola, Piergiuseppe De Berardinis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2015-04-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201404525 |
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