Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications
Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains inc...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-08-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/16/9/1114 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850259893045428224 |
|---|---|
| author | Arun Karnwal Vikas Sharma Gaurav Kumar Amar Yasser Jassim Aradhana Dohroo Iyyakkannu Sivanesan |
| author_facet | Arun Karnwal Vikas Sharma Gaurav Kumar Amar Yasser Jassim Aradhana Dohroo Iyyakkannu Sivanesan |
| author_sort | Arun Karnwal |
| collection | DOAJ |
| description | Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, cancer treatment, tissue engineering, immunotherapy, and gene therapy. Despite the transformative potential, several challenges hinder their efficacy, such as limited drug capacity, suboptimal targeting, and poor solubility. This review delves into the latest advancements in nanocarrier technologies, examining their properties, associated limitations, and the innovative solutions developed to address these issues. It highlights promising nanocarrier systems like nanocomposites, micelles, hydrogels, microneedles, and artificial cells that employ advanced conjugation techniques, sustained and stimulus-responsive release mechanisms, and enhanced solubility. By exploring these novel structures and their contributions to overcoming existing barriers, the article emphasizes the vital role of interdisciplinary research in advancing nanobiotechnology. This field offers unparalleled opportunities for precise and effective therapeutic delivery, underscoring its potential to reshape healthcare through personalized, targeted treatments and improved drug performance. |
| format | Article |
| id | doaj-art-cbfaf32c3d4b47e2906d16762e493589 |
| institution | OA Journals |
| issn | 1999-4923 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj-art-cbfaf32c3d4b47e2906d16762e4935892025-08-20T01:55:46ZengMDPI AGPharmaceutics1999-49232024-08-01169111410.3390/pharmaceutics16091114Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical ApplicationsArun Karnwal0Vikas Sharma1Gaurav Kumar2Amar Yasser Jassim3Aradhana Dohroo4Iyyakkannu Sivanesan5Department of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, IndiaDepartment of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, IndiaDepartment of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, IndiaDepartment of Marine Vertebrate, Marine Science Center, University of Basrah, Basrah 61004, IraqSchool of Agricultural Sciences, Baddi University of Emerging Sciences and Technologies, Baddi 173405, IndiaDepartment of Environmental Health Science, Institute of Natural Science and Agriculture, Konkuk University, Seoul 05029, Republic of KoreaNanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, cancer treatment, tissue engineering, immunotherapy, and gene therapy. Despite the transformative potential, several challenges hinder their efficacy, such as limited drug capacity, suboptimal targeting, and poor solubility. This review delves into the latest advancements in nanocarrier technologies, examining their properties, associated limitations, and the innovative solutions developed to address these issues. It highlights promising nanocarrier systems like nanocomposites, micelles, hydrogels, microneedles, and artificial cells that employ advanced conjugation techniques, sustained and stimulus-responsive release mechanisms, and enhanced solubility. By exploring these novel structures and their contributions to overcoming existing barriers, the article emphasizes the vital role of interdisciplinary research in advancing nanobiotechnology. This field offers unparalleled opportunities for precise and effective therapeutic delivery, underscoring its potential to reshape healthcare through personalized, targeted treatments and improved drug performance.https://www.mdpi.com/1999-4923/16/9/1114targeted drug deliverynanocarriersnovel nanostructuresprecise therapeuticsnanobiotechnologytherapeutic approaches |
| spellingShingle | Arun Karnwal Vikas Sharma Gaurav Kumar Amar Yasser Jassim Aradhana Dohroo Iyyakkannu Sivanesan Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications Pharmaceutics targeted drug delivery nanocarriers novel nanostructures precise therapeutics nanobiotechnology therapeutic approaches |
| title | Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications |
| title_full | Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications |
| title_fullStr | Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications |
| title_full_unstemmed | Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications |
| title_short | Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications |
| title_sort | transforming medicine with nanobiotechnology nanocarriers and their biomedical applications |
| topic | targeted drug delivery nanocarriers novel nanostructures precise therapeutics nanobiotechnology therapeutic approaches |
| url | https://www.mdpi.com/1999-4923/16/9/1114 |
| work_keys_str_mv | AT arunkarnwal transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications AT vikassharma transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications AT gauravkumar transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications AT amaryasserjassim transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications AT aradhanadohroo transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications AT iyyakkannusivanesan transformingmedicinewithnanobiotechnologynanocarriersandtheirbiomedicalapplications |