The miR-183/96/182 cluster regulates sensory innervation, resident myeloid cells and functions of the cornea through cell type-specific target genes

The miR-183/96/182 cluster regulates sensory innervation, resident myeloid cells and functions of the cornea through cell type-specific target genes

Abstract The conserved miR-183/96/182 cluster (miR-183C) is expressed in both corneal resident myeloid cells (CRMCs) and sensory nerves (CSN) and modulates corneal immune/inflammatory responses. To uncover cell type-specific roles of miR-183C in CRMC and CSN and their contributions to corneal physio...

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Main Authors: Naman Gupta, Mallika Somayajulu, Katherine Gurdziel, Giovanni LoGrasso, Haidy Aziz, Rita Rosati, Sharon McClellan, Ahalya Pitchaikannu, Manoranjan Santra, Muhammed Farooq Abdul Shukkur, Paul Stemmer, Linda D. Hazlett, Shunbin Xu
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58403-1
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