Semiannual Imaging Surveillance Is Associated with Better Survival in Patients with Non-B, Non-C Hepatocellular Carcinoma
Since it remains elusive whether and how the imaging surveillance affects the survival in patients with non-B, non-C hepatocellular carcinoma (NBNC-HCC), we conducted this retrospective study which investigated the association between the semiannual surveillance prior to HCC diagnosis and the surviv...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/687484 |
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| author | Kuniaki Shindo Shinya Maekawa Nobutoshi Komatsu Akihisa Tatsumi Mika Miura Mitsuaki Sato Yuichiro Suzuki Shuya Matsuda Masaru Muraoka Fumitake Amemiya Mitsuharu Fukasawa Tatsuya Yamaguchi Yasuhiro Nakayama Tomoyoshi Uetake Taisuke Inoue Minoru Sakamoto Tadashi Sato Nobuyuki Enomoto |
| author_facet | Kuniaki Shindo Shinya Maekawa Nobutoshi Komatsu Akihisa Tatsumi Mika Miura Mitsuaki Sato Yuichiro Suzuki Shuya Matsuda Masaru Muraoka Fumitake Amemiya Mitsuharu Fukasawa Tatsuya Yamaguchi Yasuhiro Nakayama Tomoyoshi Uetake Taisuke Inoue Minoru Sakamoto Tadashi Sato Nobuyuki Enomoto |
| author_sort | Kuniaki Shindo |
| collection | DOAJ |
| description | Since it remains elusive whether and how the imaging surveillance affects the survival in patients with non-B, non-C hepatocellular carcinoma (NBNC-HCC), we conducted this retrospective study which investigated the association between the semiannual surveillance prior to HCC diagnosis and the survival in patients with the initial diagnosis of HCC induced by hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infections (N=141) and non-B, non-C etiology (N=30). It was demonstrated that surveillance was less frequently performed in the NBNC-HCC patients compared to that in HCC patients with HBV and/or HCV infections (B/C-HCC patients), and the survival was unfavorable in NBNC-HCC patients. On the other hand, the survival of NBNC-HCC patients with semiannual surveillance was significantly favorable than those patients without semiannual surveillance, and the survival was similar between B/C-HCCs and NBNC-HCCs with semiannual surveillance. In conclusion, though NBNC-HCC patients compared to B/C-HCC patients had poorer prognosis overall, these NBNC-HCC patients with semiannual surveillance had a better survival almost equivalent to the survival of B/C-HCC patients with semiannual surveillance, demonstrating the clinical utility of the semiannual imaging surveillance program for NBNC-HCCs. |
| format | Article |
| id | doaj-art-cbf1ad9e7bd6411d8d12a309ddd9e8ac |
| institution | OA Journals |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-cbf1ad9e7bd6411d8d12a309ddd9e8ac2025-08-20T02:19:57ZengWileyMediators of Inflammation0962-93511466-18612015-01-01201510.1155/2015/687484687484Semiannual Imaging Surveillance Is Associated with Better Survival in Patients with Non-B, Non-C Hepatocellular CarcinomaKuniaki Shindo0Shinya Maekawa1Nobutoshi Komatsu2Akihisa Tatsumi3Mika Miura4Mitsuaki Sato5Yuichiro Suzuki6Shuya Matsuda7Masaru Muraoka8Fumitake Amemiya9Mitsuharu Fukasawa10Tatsuya Yamaguchi11Yasuhiro Nakayama12Tomoyoshi Uetake13Taisuke Inoue14Minoru Sakamoto15Tadashi Sato16Nobuyuki Enomoto17First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanFirst Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, JapanSince it remains elusive whether and how the imaging surveillance affects the survival in patients with non-B, non-C hepatocellular carcinoma (NBNC-HCC), we conducted this retrospective study which investigated the association between the semiannual surveillance prior to HCC diagnosis and the survival in patients with the initial diagnosis of HCC induced by hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infections (N=141) and non-B, non-C etiology (N=30). It was demonstrated that surveillance was less frequently performed in the NBNC-HCC patients compared to that in HCC patients with HBV and/or HCV infections (B/C-HCC patients), and the survival was unfavorable in NBNC-HCC patients. On the other hand, the survival of NBNC-HCC patients with semiannual surveillance was significantly favorable than those patients without semiannual surveillance, and the survival was similar between B/C-HCCs and NBNC-HCCs with semiannual surveillance. In conclusion, though NBNC-HCC patients compared to B/C-HCC patients had poorer prognosis overall, these NBNC-HCC patients with semiannual surveillance had a better survival almost equivalent to the survival of B/C-HCC patients with semiannual surveillance, demonstrating the clinical utility of the semiannual imaging surveillance program for NBNC-HCCs.http://dx.doi.org/10.1155/2015/687484 |
| spellingShingle | Kuniaki Shindo Shinya Maekawa Nobutoshi Komatsu Akihisa Tatsumi Mika Miura Mitsuaki Sato Yuichiro Suzuki Shuya Matsuda Masaru Muraoka Fumitake Amemiya Mitsuharu Fukasawa Tatsuya Yamaguchi Yasuhiro Nakayama Tomoyoshi Uetake Taisuke Inoue Minoru Sakamoto Tadashi Sato Nobuyuki Enomoto Semiannual Imaging Surveillance Is Associated with Better Survival in Patients with Non-B, Non-C Hepatocellular Carcinoma Mediators of Inflammation |
| title | Semiannual Imaging Surveillance Is Associated with Better Survival
in Patients with Non-B, Non-C Hepatocellular Carcinoma |
| title_full | Semiannual Imaging Surveillance Is Associated with Better Survival
in Patients with Non-B, Non-C Hepatocellular Carcinoma |
| title_fullStr | Semiannual Imaging Surveillance Is Associated with Better Survival
in Patients with Non-B, Non-C Hepatocellular Carcinoma |
| title_full_unstemmed | Semiannual Imaging Surveillance Is Associated with Better Survival
in Patients with Non-B, Non-C Hepatocellular Carcinoma |
| title_short | Semiannual Imaging Surveillance Is Associated with Better Survival
in Patients with Non-B, Non-C Hepatocellular Carcinoma |
| title_sort | semiannual imaging surveillance is associated with better survival in patients with non b non c hepatocellular carcinoma |
| url | http://dx.doi.org/10.1155/2015/687484 |
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