Alpha‐synuclein RT‐QuIC assay in gastroduodenal and skin biopsies of Parkinson disease patients

Alpha‐synuclein RT‐QuIC assay in gastroduodenal and skin biopsies of Parkinson disease patients

Abstract In this study, we compared the value of pathological alpha‐synuclein (αSyn) seed amplification assay (SAA) in gastric and duodenal biopsies with skin biopsies in Parkinson disease (PD) patients with different disease duration. The accuracy of αSyn SAA was 87.7% in skin, 67.4% in duodenum, a...

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Main Authors: Aron Emmi, Angela Mammana, Michele Sandre, Simone Baiardi, Luca Weis, Marcello Rossi, Franco Magliocchetti, Edoardo Savarino, Francesco Paolo Russo, Andrea Porzionato, Miryam Carecchio, Marta Campagnolo, Angelo Antonini, Piero Parchi
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52282
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