Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment

The presence of vitamin D receptors in small intestine muscle cells may lead one to think that vitamin D may act locally, influencing intracellular calcium concentration and contributing to the contraction-relaxation regulation of the intestinal smooth muscle cells. This study investigates the poten...

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Main Authors: Giraldi Guglielmo, Fioravanti Angelo, De Luca d’Alessandro Eugenia, Palmery Maura, Martinoli Lucia
Format: Article
Language:English
Published: Sciendo 2015-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2015-0023
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author Giraldi Guglielmo
Fioravanti Angelo
De Luca d’Alessandro Eugenia
Palmery Maura
Martinoli Lucia
author_facet Giraldi Guglielmo
Fioravanti Angelo
De Luca d’Alessandro Eugenia
Palmery Maura
Martinoli Lucia
author_sort Giraldi Guglielmo
collection DOAJ
description The presence of vitamin D receptors in small intestine muscle cells may lead one to think that vitamin D may act locally, influencing intracellular calcium concentration and contributing to the contraction-relaxation regulation of the intestinal smooth muscle cells. This study investigates the potential effects of vitamin D and calcium on intestinal motility using an in vitro test.
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institution Kabale University
issn 1846-9558
language English
publishDate 2015-09-01
publisher Sciendo
record_format Article
series Acta Pharmaceutica
spelling doaj-art-cbe8caf4e64643bfbcd450fa8923b0032025-02-02T09:57:48ZengSciendoActa Pharmaceutica1846-95582015-09-0165334334910.1515/acph-2015-0023acph-2015-0023Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatmentGiraldi Guglielmo0Fioravanti Angelo1De Luca d’Alessandro Eugenia2Palmery Maura3Martinoli Lucia4 Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy Department of Physiology and Pharmacology, V. Erspamer Sapienza University of Rome, Italy Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy Department of Physiology and Pharmacology, V. Erspamer Sapienza University of Rome, Italy Department of Physiology and Pharmacology, V. Erspamer Sapienza University of Rome, ItalyThe presence of vitamin D receptors in small intestine muscle cells may lead one to think that vitamin D may act locally, influencing intracellular calcium concentration and contributing to the contraction-relaxation regulation of the intestinal smooth muscle cells. This study investigates the potential effects of vitamin D and calcium on intestinal motility using an in vitro test.https://doi.org/10.1515/acph-2015-0023vitamin dcalciumintestinal motilityin vitro tests
spellingShingle Giraldi Guglielmo
Fioravanti Angelo
De Luca d’Alessandro Eugenia
Palmery Maura
Martinoli Lucia
Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
Acta Pharmaceutica
vitamin d
calcium
intestinal motility
in vitro tests
title Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
title_full Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
title_fullStr Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
title_full_unstemmed Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
title_short Investigation of the effects of vitamin D and calcium on intestinal motility: In vitro tests and implications for clinical treatment
title_sort investigation of the effects of vitamin d and calcium on intestinal motility in vitro tests and implications for clinical treatment
topic vitamin d
calcium
intestinal motility
in vitro tests
url https://doi.org/10.1515/acph-2015-0023
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AT fioravantiangelo investigationoftheeffectsofvitamindandcalciumonintestinalmotilityinvitrotestsandimplicationsforclinicaltreatment
AT delucadalessandroeugenia investigationoftheeffectsofvitamindandcalciumonintestinalmotilityinvitrotestsandimplicationsforclinicaltreatment
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